ArticleFrontiers in public health2022
The Effect of Thunder-Fire Moxibustion on Lumbar Disc Herniation: Study Protocol for a Randomized Controlled Trial.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.
- The efficacy and safety of endoscopic surgery combined with platelet-rich plasma for lumbar disk herniation: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Efficacy of acupoint-related therapies for nausea and vomiting in pregnancy: a Bayesian network meta-analysis.Frontiers in medicine · 2025Pooled it
- Comparative effectiveness of moxibustion-based combination therapies for lumbar disc herniation: a systematic review and network meta-analysis of 50 randomized trials.Frontiers in neurologyPooled it
- Clinical Efficacy and Safety of a Modified Moxibustion Therapy for Low Back Pain in Lumbar Disc Herniation: A Two-Center, Randomized, Controlled, Non-Inferiority Trial.Journal of pain research · 2024Trial
- Computed tomography-guided oxygen-ozone injection for the treatment of lumbar disc herniation complicated with lumbar spinal stenosis.Medical gas research · 2026Article
- Correlation between lumbar disc herniation nerve root compression and clinical symptoms: a study using lumbosacral plexus magnetic resonance neurography combined with T2 mapping.BMC musculoskeletal disorders · 2026Article
- Comparative efficacy of moxibustion in chemotherapy-induced leukopenia: A Bayesian network meta-analysis.Integrative medicine research · 2025Review
- Progress in the research of thunder-fire moxibustion and warm acupunct ure-moxibustion combined with western medicine in treating knee osteoarthritis.Pakistan journal of medical sciences · 2025Review
- Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial protocol.Frontiers in neurology · 2025Article
- Acupotomy for Musculoskeletal Pain: Exploring Therapeutic Potential and Future Directions.Journal of pain research · 2025Article
- Traditional Chinese Rehabilitation Exercise (TCRE) for Myofascial Pain: Current Evidence and Further Challenges.Journal of pain research · 2024Review
- Enhancing Surgical Pain Management Through Innovative Nerve Block Techniques [Letter].Journal of pain research · 2024Article
- Governor vessel moxibustion for cancer-related fatigue in colorectal patients: a randomized trial.Frontiers in oncology · 2023Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Lumbar disc herniation (LDH) is a common disease seen in orthopedics; it is caused by nucleus pulposus herniation. Its clinical manifestations are low back pain, radiating pain of the lower limbs, and cauda equina symptoms that seriously affect patients' quality of life. At present, oral analgesics are commonly used in the treatment of LDH; but they can produce gastrointestinal reactions and other side effects. Thunder-fire moxibustion is a method that is widely used in China to treat pain syndromes. This study aimed to design a randomized controlled trial to explore the effectiveness and safety of thunder-fire moxibustion in the treatment of lumbar disc herniation. Methods: Ninety patients will be enrolled and randomly divided into one of two groups: the thunder-fire moxibustion group and the acetaminophen group. The thunder-fire moxibustion group will be treated with moxa sticks at BL25, GV3, BL23, and GV4; and after 15 min of local whirling moxibustion, the contralateral acupoints will be treated with moxibustion for 15 min. The study period will include two 10-day courses of treatment, for a total study duration of 20 days. The acetaminophen group participants will take one acetaminophen sustained-release tablet twice a day for the duration of the study period. In contrast, the thunder-fire moxibustion group participants will be treated with thunder-fire moxibustion every other day for 30 min. The primary outcome will be the Japanese Orthopedic Association (JOA) score. Visual analog scale (VAS) and Oswestry Disability Index (ODI) will be used as the secondary outcome measures. Adverse events (AEs) will also be recorded. Assessments will be conducted at baseline, the end of the first and second courses of treatment. Discussion: This study will determine whether thunder-fire moxibustion is more effective and safer than acetaminophen in the treatment of patients with LDH. Trial Registration: Chinese Clinical Trial Registry (http://www.chictr.org.cn), ChiCTR2000036079.
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