Evidence map›Paper›PMID 35874948›Full record

ArticleInternational journal of biological sciences2022

Prospects of Coffee Leaf against SARS-CoV-2 Infection.

Chen-Shiou Wu, Hsiu-Mei Chiang, Yeh Chen, Chung-Yu Chen, Hsiao-Fan Chen, Wen-Chi Su, Wei-Jan Wang, Yu-Chi Chou, Wei-Chao Chang, Shao-Chun Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
  7. Antimicrobial and Antibiofilm Activity ofMolecules (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. International journal of molecular sciences · 2023
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Chen-Shiou WuGraduate Institute of Biomedical Sciences, China Medical University, Taichung 406040, Taiwan.
Hsiu-Mei ChiangDepartment of Cosmeceutics, China Medical University, Taichung 406040, Taiwan.
Yeh ChenGraduate Institute of Biomedical Sciences, China Medical University, Taichung 406040, Taiwan.
Chung-Yu ChenResearch Center for Cancer Biology, China Medical University, Taichung 406040, Taiwan.
Hsiao-Fan ChenGraduate Institute of Biomedical Sciences, China Medical University, Taichung 406040, Taiwan.
Wen-Chi SuGraduate Institute of Biomedical Sciences, China Medical University, Taichung 406040, Taiwan.
Wei-Jan WangResearch Center for Cancer Biology, China Medical University, Taichung 406040, Taiwan.
Yu-Chi ChouBiomedical Translation Research Center (BioTReC), Academia Sinica, Taipei 115024, Taiwan.
Wei-Chao ChangCenter for Molecular Medicine, China Medical University Hospital, China Medical University, Taichung 404332, Taiwan.
Shao-Chun WangGraduate Institute of Biomedical Sciences, China Medical University, Taichung 406040, Taiwan.
Mien-Chie HungGraduate Institute of Biomedical Sciences, China Medical University, Taichung 406040, Taiwan.
China Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the current climate, many countries are in dire need of effective preventive methods to curb the Severe Acute Respiratory Syndrome Coronavirus Type 2 (SARS-CoV-2) pandemic. The purpose of this research is to screen and explore natural plant extracts that have the potential to against SARS-CoV-2 and provide alternative options for SARS-CoV-2 prevention and hand sanitizer or spray-like disinfectants. We first used Spike-ACE2 ELISA and TMPRSS2 fluorescence resonance energy transfer (FRET) assays to screen extracts from agricultural by-products from Taiwan with the potential to impede SARS-CoV-2 infection. Next, the SARS-CoV-2 pseudo-particles (Vpp) infection assay was tested to validate the effectiveness. We identified an extract from coffee leaf (

Indexed as

CoffeaCOVID-19Hand SanitizersPlant ExtractsAngiotensin-Converting Enzyme 2SARS-CoV-2Spike Glycoprotein, CoronavirusAngiotensin-Converting Enzyme 2Hand SanitizersPlant ExtractsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2ACE2Coffee leafSARS-CoV-2skinSpike

Identifiers

PMID35874948
PMCPMC9305275
OpenAlexW4285821059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.