Integrated case-based clinical approach in understanding pathways, complexities, pitfalls and challenges in neurodegenerative disorders.

Aashitha Dhavala, Aditya Samitinjay, Praveen Khairkar, Vivek Podder, Amy Price, Syeda Hira Fatima, Rakesh Biswas

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In one paragraph

Article in American journal of neurodegenerative disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.1field-weighted citation impact, top 52% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Aashitha DhavalaJunior Resident in General Medicine, Kamineni Institute of Medical Sciences Narketpally, India.

Aditya SamitinjaySenior Resident in General Medicine, Government General & Chest Hospital Erragada, Hyderabad, India.

Praveen KhairkarHOD & Professor in Psychiatry, Kamineni Institute of Medical Sciences Narketpally, India.

Vivek PodderVisiting Lecturer, The University of Adelaide Australia.

Amy PriceSenior Research Scientist Stanford School of Medicine CA, USA.

Syeda Hira FatimaJunior Resident in Psychiatry, Kamineni Institute of Medical Sciences Narketpally, India.

Rakesh BiswasHOD & Professor in General Medicine, Kamineni Institute of Medical Sciences Narketpally 508254, India.

Kamineni Institute of Dental Sciences · INGovernment Nizamia General Hospital · INStanford Medicine · USThe University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis paper presents 5 cases of neurodegenerative disorders from our tertiary care rural hospital in south India. The purpose of this paper is to generate an emerging common theme by thematic analysis of clinical data from each of these patients. A theme emerged, we identified that there was a common clinical ground in patients with movement disorders and psychiatric symptoms. From this common theme, these patients eventually went on to develop different courses of illnesses. METHODOLOGY: Clinical analysis of a case series of 5 patients with neurodegenerative disorders attending the Medicine or Psychiatry services of our hospital.

conclusionA clear & consistent association between movement disorders and psychiatric symptoms was found. Although our data is limited, we conclude that movement disorders can be early clinical markers of organic psychopathology. However, we are aware that this association can be confounded by substance abuse, stress, sleep disruption and even therapeutic interventions, and thus these factors were accounted for and yet we conclude that movement disorders can be early clinical indictors of organic psychopathology.

Indexed as

case-based blended learning ecosystemmovement disordersNeurodegenerative disordersorganic psychopathologyParkinson’s disease

Identifiers

PMID35874938

PMCPMC9301093

OpenAlexW4288064402

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.