ArticleApplied physics. A, Materials science & processing2022
Surface modified chitosan-silica nanocomposite porous thin film based multi-parametric optical glucose sensor.
Article in Applied physics. A, Materials science & processing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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3 authors.
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Abstract
In this work, a multi-parametric optical sensor based on chitosan-silica nanocomposite (CSNC) porous thin film has been developed for effective detection of glucose in pathological range. The CSNC films were surface functionalized with Glucose Oxidase enzyme via Glutaraldehyde crosslinking chains for better attachment of enzyme molecules on thin film surface. FESEM and FTIR were performed for morphological and compositional characterisation of the composite films. Five interlinked optical parameters, i.e., transmittance (T), reflectance (R), internal scattering (IS), surface scattering (SS) and output power (OP) were measured simultaneously using image processing environment for cost efficiency of the system. Effect of surface functionalization on individual parameter response was studied. It was observed that without surface functionalization only two parameters change significantly, while surface functionalization enables all five parameters. For lower and higher glucose concentration (< 17 mM and > 17 mM), IS and SS were found to be maximum sensitive among the five parameters, respectively. Maximum sensitivity of 1.2 mM
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