Evidence map›Paper›PMID 35874852›Full record

ArticlePulmonary circulation2022

The role of macrophages in right ventricular remodeling in experimental pulmonary hypertension.

Sue Gu, Claudia Mickael, Rahul Kumar, Michael H Lee, Linda Sanders, Biruk Kassa, Julie Harral, Jason Williams, Kirk C Hansen, Kurt R Stenmark and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Sue GuDepartment of Medicine, Division of Pulmonary Sciences and Critical Care Medicine University of Colorado Anschutz Medical Campus Aurora Colorado USA.ORCID 0000-0002-2719-623X
Claudia MickaelDepartment of Medicine, Division of Pulmonary Sciences and Critical Care Medicine University of Colorado Anschutz Medical Campus Aurora Colorado USA.
Rahul KumarDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Zuckerberg San Francisco General Hospital and Trauma Center University of California San Francisco California USA.
Michael H LeeDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Zuckerberg San Francisco General Hospital and Trauma Center University of California San Francisco California USA.ORCID 0000-0002-5739-8369
Linda SandersDepartment of Medicine, Division of Pulmonary Sciences and Critical Care Medicine University of Colorado Anschutz Medical Campus Aurora Colorado USA.
Biruk KassaDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Zuckerberg San Francisco General Hospital and Trauma Center University of California San Francisco California USA.
Julie HarralCardiovascular Pulmonary Research Lab University of Colorado School of Medicine Aurora Colorado USA.
Jason WilliamsBiochemistry and Molecular Genetics University of Colorado Anschutz Medical Campus Aurora Colorado USA.ORCID 0000-0002-8023-2607
Kirk C HansenBiochemistry and Molecular Genetics University of Colorado Anschutz Medical Campus Aurora Colorado USA.
Kurt R StenmarkCardiovascular Pulmonary Research Lab University of Colorado School of Medicine Aurora Colorado USA.
Rubin M TuderDepartment of Medicine, Division of Pulmonary Sciences and Critical Care Medicine University of Colorado Anschutz Medical Campus Aurora Colorado USA.
Brian B GrahamDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Zuckerberg San Francisco General Hospital and Trauma Center University of California San Francisco California USA.ORCID 0000-0001-7541-2585
University of Colorado Anschutz Medical Campus · USSan Francisco General Hospital · USUniversity of Colorado Denver · US

Funding

MULTIDISCIPLINARY RESPIRATORY DISEASES RESEARCH TRAININGT32HL007085 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM, LISA A MAIER · 1985 to 2026
$21.6M
Role of Complement-Driven Pulmonary Vascular Inflammation in PHP01HL152961 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI TUDER, RUBIN M. · 2020 to 2024
$14.1M
Translational Pulmonary Vascular Biology ProgramT32HL007171 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Sonia Castro Flores, Tim Lahm · 1985 to 2026
$9.4M
Investigating paclitaxel treatment in a pre-clinical model of Schistosoma-pulmonary hypertensionR01HL135872 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Brian Barkley Graham · 2017 to 2026
$5.1M
PRIDE Academy: Impact of Ancestry and Gender to omics of lung diseasesR25HL146166 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Matthew Wayne DeCamp, Sonia Castro Flores · 2019 to 2026
$3.4M
Quadrupole-Orbitrap Mass SpectrometerS10OD021641 · OD · UNIVERSITY OF COLORADO DENVER · PI HANSEN, KIRK C · 2017 to 2017
$600k
The Role of Smooth Muscle Cell Fatty Acid Oxidation in the Pathogenesis of Pulmonary HypertensionF32HL151076 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEE, MICHAEL HYUNJEAN · 2020 to 2022
$99k
BLRD VA I01 BX002042NHLBI NIH HHS F32 HL151076NHLBI NIH HHS P01 HL152961NHLBI NIH HHS R01 HL135872NHLBI NIH HHS R25 HL146166NHLBI NIH HHS T32 HL007085NHLBI NIH HHS T32 HL007171NIAID NIH HHS HHSN272201000005CNIAID NIH HHS HHSN272201000005INIH HHS S10 OD021641
6 · The paper itself

Abstract

Right ventricular (RV) failure is the primary cause of death in pulmonary hypertension (PH), but the mechanisms of RV failure are not well understood. We hypothesized macrophages in the RV contribute to the RV response in PH. We induced PH in mice with hypoxia (FiO

Indexed as

adaptationhypoxiainflammationright heartSchistosoma

Identifiers

PMID35874852
PMCPMC9297026
OpenAlexW4283525703

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.