Evidence map›Paper›PMID 35874769›Full record

ArticleFrontiers in immunology2022

γ9δ2 T-Cell Expansion and Phenotypic Profile Are Reflected in the CDR3δ Repertoire of Healthy Adults.

Anna Vyborova, Anke Janssen, Lucrezia Gatti, Froso Karaiskaki, Austin Yonika, Sanne van Dooremalen, Jasper Sanders, Dennis X Beringer, Trudy Straetemans, Zsolt Sebestyen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Mechanisms and Applications of γδ T Cells in Anti-Tumor Immunity.Cancer control : journal of the Moffitt Cancer Center
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Anna VyborovaCenter for Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, Netherlands.
Anke JanssenCenter for Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, Netherlands.
Lucrezia GattiCenter for Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, Netherlands.
Froso KaraiskakiCenter for Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, Netherlands.
Austin YonikaCenter for Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, Netherlands.
Sanne van DooremalenCenter for Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, Netherlands.
Jasper SandersCenter for Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, Netherlands.
Dennis X BeringerCenter for Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, Netherlands.
Trudy StraetemansCenter for Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, Netherlands.
Zsolt SebestyenCenter for Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, Netherlands.
Jürgen KuballCenter for Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, Netherlands.
Utrecht University · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

γ9δ2T cells fill a distinct niche in human immunity due to the unique physiology of the phosphoantigen-reactive γ9δ2TCR. Here, we highlight reproducible TCRδ complementarity-determining region 3 (CDR3δ) repertoire patterns associated with γ9δ2T cell proliferation and phenotype, thus providing evidence for the role of the CDR3δ in modulating

Indexed as

Complementarity Determining RegionsT-LymphocytesAdultCell ProliferationHumansPhenotypeComplementarity Determining Regionsadult Vδ2 repertoireCD94/NKG2A(B)CDR3δdifferentiation profilehuman γ9δ2 T cellsNKG2Dpublic clonotypes

Identifiers

PMID35874769
PMCPMC9301380
OpenAlexW4284707802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.