Evidence map›Paper›PMID 35874711›Full record

ArticleFrontiers in immunology2022

Beneficial Bacteria in the Intestines of Housefly Larvae Promote Larval Development and Humoral Phenoloxidase Activity, While Harmful Bacteria do the Opposite.

Qian Zhang, Shumin Wang, Xinyu Zhang, Kexin Zhang, Ying Li, Yansong Yin, Ruiling Zhang, Zhong Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 40 citations in OpenAlex.

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  8. A taste of one's own medicine:Frontiers in immunology · 2025
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  9. Review
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  16. Effect of host shift on the gut microbes ofFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Qian ZhangSchool of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Taian, China.
Shumin WangSchool of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Taian, China.
Xinyu ZhangSchool of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Taian, China.
Kexin ZhangSchool of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Taian, China.
Ying LiSchool of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Taian, China.
Yansong YinSchool of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Taian, China.
Ruiling ZhangSchool of Basic Medical Science, Shandong First Medical University (Shandong Academy of Medical Sciences), Taian, China.
Zhong ZhangThe First Affiliated Hospital of Shandong First Medical University, Jinan, China.
Shandong First Medical University · CNAffiliated Hospital of Shandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microenvironment of houseflies provides unique conditions for microbial colonization. Some gut microorganisms provide benefits for the development of the host by regulating the interaction between the host and intestinal pathogens. Gut microbial alterations can stimulate the host's immune mechanism to resist pathogen invasion and affect the development of insects. In this study, we isolated 10 bacterial strains from housefly larval intestines. The isolated bacteria were added to the larval diet to analyze the effects of microecological regulation of gut bacteria on larval development. Dynamic changes in gut flora composition after oral administration of specific bacteria were analyzed although 16S rRNA gene high-throughput sequencing technology. To explore the interaction between gut bacteria and the host, the immune response of larvae against the invasion of foreign microorganisms was observed through a phenoloxidase activity experiment. Our results showed that the oral administration of various isolated bacteria had different effects on larval development. Oral administration of beneficial bacteria, including

Indexed as

HousefliesAnimalsBacteriaIntestinesLarvaMonophenol MonooxygenaseRNA, Ribosomal, 16SMonophenol MonooxygenaseRNA, Ribosomal, 16S16S rRNAgut bacteriahouseflyhumoral immunityphenoloxidase

Identifiers

PMID35874711
PMCPMC9299419
OpenAlexW4286631621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.