Evidence map›Paper›PMID 35874707›Full record

ArticleFrontiers in immunology2022

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Riikka Viitanen, Helena Virtanen, Heidi Liljenbäck, Olli Moisio, Xiang-Guo Li, Valeria Nicolini, Marine Richard, Christian Klein, Tapan Nayak, Sirpa Jalkanen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Riikka ViitanenTurku PET Centre, University of Turku, Turku, Finland.
Helena VirtanenTurku PET Centre, University of Turku, Turku, Finland.
Heidi LiljenbäckTurku PET Centre, University of Turku, Turku, Finland.
Olli MoisioTurku PET Centre, University of Turku, Turku, Finland.
Xiang-Guo LiTurku PET Centre, University of Turku, Turku, Finland.
Valeria NicoliniRoche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Marine RichardRoche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Christian KleinRoche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland.
Tapan NayakRoche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
Sirpa JalkanenInFLAMES Research Flagship Center, University of Turku, Turku, Finland.
Anne RoivainenTurku PET Centre, University of Turku, Turku, Finland.
Roche (Switzerland) · CHUniversity of Turku · FITurku PET Centre · FITurku University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular adhesion protein-1 (VAP-1) is an inflammation-inducible adhesion molecule, which supports contact between leukocytes and inflamed endothelium. There is evidence that VAP-1 is involved in the recruitment of leukocytes to melanoma tumors. Interleukin-2 (IL-2)-based immunotherapy is an efficient therapy that promotes immune system activity against cancers but is associated with toxicity. In the present study, we evaluated the feasibility of PET/CT imaging using the radiotracer [

Indexed as

Gallium RadioisotopesMelanoma, ExperimentalAnimalsCD8-Positive T-LymphocytesHeterocyclic Compounds, 1-RingImmunologic FactorsImmunotherapyInterleukin-2MicePositron Emission Tomography Computed TomographySialic Acid Binding Immunoglobulin-like Lectins1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidGallium RadioisotopesHeterocyclic Compounds, 1-RingImmunologic FactorsInterleukin-2Sialic Acid Binding Immunoglobulin-like Lectinsfibroblast activation proteinimmunocytokineinterleukin 2 (IL-2)melanomaPET

Identifiers

PMID35874707
PMCPMC9298541
OpenAlexW4283828799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.