Evidence map›Paper›PMID 35874595›Full record

ArticleFrontiers in pediatrics2022

Collapsing Focal Segmental Glomerulosclerosis in Siblings With Compound Heterozygous Variants in

Rachel K Cason, Anna Williams, Megan Chryst-Stangl, Guanghong Wu, Kinsie Huggins, Kaye E Brathwaite, Brandon M Lane, Larry A Greenbaum, Vivette D D'Agati, Rasheed A Gbadegesin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Nucleoporin-associated steroid-resistant nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Collapsing glomerulopathy: unraveling varied pathogeneses.Current opinion in nephrology and hypertension · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Rachel K CasonDivision of Nephrology, Department of Pediatrics, Duke University Medical Center, Durham, NC, United States.
Anna WilliamsDivision of Nephrology, Department of Pediatrics, Duke University Medical Center, Durham, NC, United States.
Megan Chryst-StanglDivision of Nephrology, Department of Pediatrics, Duke University Medical Center, Durham, NC, United States.
Guanghong WuDivision of Nephrology, Department of Pediatrics, Duke University Medical Center, Durham, NC, United States.
Kinsie HugginsDivision of Nephrology, Department of Pediatrics, Duke University Medical Center, Durham, NC, United States.
Kaye E BrathwaiteDivision of Pediatric Nephrology, Children's Hospital at Montefiore, The Bronx, NY, United States.
Brandon M LaneDivision of Nephrology, Department of Pediatrics, Duke University Medical Center, Durham, NC, United States.
Larry A GreenbaumDivision of Pediatric Nephrology, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, United States.
Vivette D D'AgatiDepartment of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, United States.
Rasheed A GbadegesinDivision of Nephrology, Department of Pediatrics, Duke University Medical Center, Durham, NC, United States.
Duke Medical Center · USChildren's Hospital at Montefiore · USColumbia University Irving Medical Center · USEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Focal segmental glomerulosclerosis (FSGS) is a major cause of end stage kidney disease, with the collapsing form having the worst prognosis. Study of families with hereditary FSGS has provided insight into disease mechanisms. Methods: In this report, we describe a sibling pair with Results: We identified segregating compound heterozygous Conclusion: To the best of our knowledge, this is the first report of cFSGS in patients with

Indexed as

APOL1collapsing FSGSfocal segmental glomerulosclerosisnephrotic syndromenucleoporin genes

Identifiers

PMID35874595
PMCPMC9301271
OpenAlexW4284692799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.