Evidence map›Paper›PMID 35874537›Full record

ArticleFrontiers in physiology2022

New Insights on Bone Tissue and Structural Muscle-Bone Unit in Constitutional Thinness.

Mélina Bailly, Audrey Boscaro, Thierry Thomas, Léonard Féasson, Frédéric Costes, Bruno Pereira, Jorg Hager, Bruno Estour, Bogdan Galusca, Lore Metz and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Mélina BaillyUniversité Clermont Auvergne, CRNH, AME2P, Clermont-Ferrand, France.
Audrey BoscaroUniversité Clermont Auvergne, CRNH, AME2P, Clermont-Ferrand, France.
Thierry ThomasDepartment of Rheumatology, Hôpital Nord, CHU, Saint-Étienne, France.
Léonard FéassonInter-University Laboratory of Human Movement Biology (LIBM) EA 7424, Jean Monnet University, Saint-Étienne, France.
Frédéric CostesDepartment of Sport Medicine and Functional Explorations, CHU, Clermont-Ferrand, France.
Bruno PereiraBiostatistics Unit, Délégation à la Recherche Clinique et à l'Innovation (DRCI), Clermont-Ferrand, France.
Jorg HagerMetabolic Health Nestlé Research, Lausanne, Switzerland.
Bruno EstourEating Disorders Addictions and Extreme Bodyweight Research Group (TAPE) EA 7423, Jean Monnet University, Saint-Étienne, France.
Bogdan GaluscaEating Disorders Addictions and Extreme Bodyweight Research Group (TAPE) EA 7423, Jean Monnet University, Saint-Étienne, France.
Lore MetzUniversité Clermont Auvergne, CRNH, AME2P, Clermont-Ferrand, France.
Daniel CourteixUniversité Clermont Auvergne, CRNH, AME2P, Clermont-Ferrand, France.
David ThivelUniversité Clermont Auvergne, CRNH, AME2P, Clermont-Ferrand, France.
Julien VerneyUniversité Clermont Auvergne, CRNH, AME2P, Clermont-Ferrand, France.
Natacha GermainEating Disorders Addictions and Extreme Bodyweight Research Group (TAPE) EA 7423, Jean Monnet University, Saint-Étienne, France.
Université Clermont Auvergne · FRCentre Hospitalier Universitaire de Saint-Étienne · FRUniversité Claude Bernard Lyon 1 · FRCentre Hospitalier Universitaire de Clermont-Ferrand · FRInstitut Génétique, Reproduction et Développement · FRNestlé (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While few studies pointed out low bone mineral densities in constitutionally thin women, little is known about potential explanations. The objective was to further explore bone architecture in both women and men with constitutional thinness to investigate their mechanical muscle-bone coupling (or uncoupling). Thirty constitutionally thin people and 31 normal weight controls participated in the study. Body composition, hip structural analysis, and trabecular bone score were assessed by dual-energy X-ray absorptiometry, bone architecture using high-resolution peripheral quantitative computed tomography, and muscle explorations through histological staining on muscle biopsies. Thirty-two out of the 48 indexes relative to density, geometry, texture, and architecture of bones were found significantly lower (

Indexed as

bone microarchitectureconstitutional thinnessmechanical interactionmuscle-bone unitskeletal muscleweight gain resistance

Identifiers

PMID35874537
PMCPMC9305386
OpenAlexW4284894014

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.