Evidence map›Paper›PMID 35874444›Full record

ArticleCase reports in medicine2022

MuSK-Myasthenia Gravis Unmasked by Hydroxychloroquine.

Shalini Bhaskar, Mohammed Fauzi Bin Abdul Rani

Abstract readCase Reports
In one paragraph

Article in Case reports in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shalini BhaskarDepartment of Medicine, Universiti Teknologi MARA, Thomson Hospital Kota Damansara, Shah Alam, Malaysia.ORCID https://orcid.org/0000-0002-9169-4209
Mohammed Fauzi Bin Abdul RaniDepartment of Medicine, Universiti Teknologi MARA, Thomson Hospital Kota Damansara, Shah Alam, Malaysia.ORCID https://orcid.org/0000-0001-7138-7642

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Muscle-specific tyrosine kinase (MuSK) antibody positive myasthenia gravis (MuSK-MG) is a rare clinical disorder, and diagnosing it can be challenging. Most of the patients present with predominant facial, oculo-bulbar, and neck muscle weakness along with respiratory muscle involvement. Such a presentation can be mistaken for bulbar onset motor neuron disease or as one of the rare oculopharyngeal myopathies. Conclusion: This report proves that MuSK-MG can also be unmasked by HCQ administration. Awareness of drug-induced/-unmasked MG is important, as failure to do so may result in a severe morbidity and a fatal outcome. The offending drug has to be promptly discontinued, and appropriate treatment should be instituted.

Identifiers

PMID35874444
PMCPMC9307397

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.