Evidence map›Paper›PMID 35874186›Full record

ArticleCluster computing2023

Deep learning application detecting SARS-CoV-2 key enzymes inhibitors.

Leila Benarous, Khedidja Benarous, Ghulam Muhammad, Zulfiqar Ali

Open access · bronzeAbstract read
In one paragraph

Article in Cluster computing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Leila BenarousLIM Laboratory (Laboratoire d'informatique Et de Mathématique), Department of Computer Science, Faculty of Science, University of Amar Telidji, Laghouat, Algeria.ORCID 0000-0003-0312-3922
Khedidja BenarousScience Fundamental Laboratory, Department of Biology, Faculty of Sciences, University of Amar Telidji, Laghouat, Algeria.ORCID 0000-0001-9112-6730
Ghulam MuhammadDepartment of Computer Engineering, College of Computer and Information Sciences, King Saud University, Riyadh, 11543 Saudi Arabia.ORCID 0000-0002-9781-3969
Zulfiqar AliSchool of Computer Science and Electronic Engineering, University of Essex, Colchester, CO4 3SQ UK.
King Saud University · SAUniversité Paris-Est Créteil · FRUniversity of Essex · GBUniversity of Laghouat · DZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fast spread of the COVID-19 over the world pressured scientists to find its cures. Especially, with the disastrous results, it engendered from human life losses to long-term impacts on infected people's health and the huge financial losses. In addition to the massive efforts made by researchers and medicals on finding safe, smart, fast, and efficient methods to accurately make an early diagnosis of the COVID-19. Some researchers focused on finding drugs to treat the disease and its symptoms, others worked on creating effective vaccines, while several concentrated on finding inhibitors for the key enzymes of the virus, to reduce its spreading and reproduction inside the human body. These enzymes' inhibitors are usually found in aliments, plants, fungi, or even in some drugs. Since these inhibitors slow and halt the replication of the virus in the human body, they can help fight it at an early stage saving the patient from death risk. Moreover, if the human body's immune system gets rid of the virus at the early stage it can be spared from the disastrous sequels it may leave inside the patient's body. Our research aims to find aliments and plants that are rich in these inhibitors. In this paper, we developed a deep learning application that is trained with various aliments, plants, and drugs to detect if a component contains SARS-CoV-2 key inhibitor(s) intending to help them find more sources containing these inhibitors. The application is trained to identify various sources rich in thirteen coronavirus-2 key inhibitors. The sources are currently just aliments, plants, and seeds and the identification is done by their names.

Indexed as

AlimentsCOVID-19Deep learningIdentificationKey enzymes inhibitorsPlants

Identifiers

PMID35874186
PMCPMC9295888
OpenAlexW4285799580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.