Evidence map›Paper›PMID 35874185›Full record

ArticleCurrent opinion in biomedical engineering2022

Bioengineering Approaches to Improve Gynecological Cancer Outcomes.

Ali Abbaspour, Andrea L Casillas, Stephanie M McGregor, Pamela K Kreeger

Abstract read
In one paragraph

Article in Current opinion in biomedical engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Organoid technology in cervical cancer research.American journal of cancer research · 2025
    Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ali AbbaspourDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin.
Andrea L CasillasDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin.
Stephanie M McGregorUniversity of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Pamela K KreegerDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin.

Funding

The role of multi-cellular aggregates vs. individual tumor cells in metastasis of high-grade serous ovarian cancerR01CA240965 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI KREEGER, PAMELA K · 2020 to 2025
$2.7M
Engineered ECM platforms to analyze progression in high grade serous ovarian cancerR01CA232517 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CAMPAGNOLA, PAUL J, KREEGER, PAMELA K · 2018 to 2022
$2.4M
Soluble and mechanical factors directing mesothelial cell migration in clearance during ovarian cancer metastasisR21CA227922 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI KREEGER, PAMELA K, NOTBOHM, JACOB K · 2019 to 2020
$359k
NCI NIH HHS R01 CA232517NCI NIH HHS R01 CA240965NCI NIH HHS R21 CA227922
6 · The paper itself

Abstract

Gynecological cancers are diagnosed in over a million females worldwide, with ovarian, endometrial (uterine), and cervical the most common. Here, we highlight recent progress by bioengineers to improve screening and diagnosis for these diseases, including potential point-of-care approaches. We provide particular attention to the use of tissue engineering, biomaterials, microfluidics, and organoids to identify mechanisms regulating disease progression and predict therapeutic responses. We also highlight opportunities for engineers to address the racial/ethnic/geographic disparities that continue to impact gynecological cancer outcomes. A challenge to improve outcomes for all gynecological cancers will be to expand the diversity of patients included in basic/clinical research to better capture the confounding effects of social/economic variables on disease progression.

Identifiers

PMID35874185
PMCPMC9307061

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.