Evidence map›Paper›PMID 35874156›Full record

ArticleFrontiers in human neuroscience2022

Transcranial Magnetic Stimulation for Long-Term Smoking Cessation: Preliminary Examination of Delay Discounting as a Therapeutic Target and the Effects of Intensity and Duration.

Alina Shevorykin, Ellen Carl, Martin C Mahoney, Colleen A Hanlon, Amylynn Liskiewicz, Cheryl Rivard, Ronald Alberico, Ahmed Belal, Lindsey Bensch, Darian Vantucci and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03865472 (Enhancing Relapse Prevention With rTMS), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03865472 naactive not recruitingnot on this map

Enhancing Relapse Prevention With rTMS: Dose-Response Parameters for Smoking Cessation

TypeinterventionalSponsorRoswell Park Cancer InstituteRan2018 to 2026Enrolled206ConditionsCigarette Smoker, Current Every Day Smoker, Current SmokerArmsQuestionnaire Administration, Repetitive Transcranial Magnetic Stimulation, Sham Intervention
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Comparing neuromodulation targets to reduce cigarette craving and withdrawal: a randomized clinical trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Alina ShevorykinRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Ellen CarlRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Martin C MahoneyRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Colleen A HanlonWake Forest School of Medicine, Winston-Salem, NC, United States.
Amylynn LiskiewiczRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Cheryl RivardRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Ronald AlbericoRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Ahmed BelalRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Lindsey BenschRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Darian VantucciRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Hannah ThornerRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Matthew MarionRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Warren K BickelFralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, United States.
Christine E ShefferRoswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Roswell Park Comprehensive Cancer Center · USBiomedical Research Institute · USWake Forest University · US

Funding

Enhancing Relapse Prevention with rTMS: Dose-Response Parameters for Smoking CessationR01CA229415 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI SHEFFER, CHRISTINE ELIZABETH · 2018 to 2022
$3.0M
NCI NIH HHS R01 CA229415
6 · The paper itself

Abstract

Background: Repetitive transcranial magnetic stimulation (rTMS) is a novel treatment for smoking cessation and delay discounting rate is novel therapeutic target. Research to determine optimal therapeutic targets and dosing parameters for long-term smoking cessation is needed. Due to potential biases and confounds introduced by the COVID-19 pandemic, we report preliminary results from an ongoing study among participants who reached study end prior to the pandemic. Methods: In a 3 × 2 randomized factorial design, participants ( Results: A large effect size was found for Duration and a medium for Intensity for latency to relapse. Increasing Duration increased the odds of abstinence 7-8-fold while increasing Intensity doubled the odds of abstinence. A large effect size was found for Duration, a small for Intensity for delay discounting rate. Increasing Duration and Intensity had a small effect on participant burden. Conclusion: Findings provide preliminary support for delay discounting as a therapeutic target and for increasing Duration and Intensity to achieve larger effect sizes for long-term smoking cessation and will provide a pre-pandemic comparison for data collected during the pandemic. Clinical Trial Registration: [www.ClinicalTrials.gov], identifier [NCT03865472].

Indexed as

brain stimulationdelay discountingself-regulationsmoking cessationtobacco dependence treatmenttranscranial magnetic stimulation

Identifiers

PMID35874156
PMCPMC9300313
OpenAlexW4286634490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.