Evidence map›Paper›PMID 35873862›Full record

ArticleInternational journal of cardiology. Heart & vasculature2022

Serial changes of coronary flow reserve over one year after transcatheter aortic valve implantation in patients with severe aortic stenosis.

Teruaki Wada, Yasutsugu Shiono, Kentaro Honda, Daisuke Higashioka, Akira Taruya, Masahiro Takahata, Suwako Fujita, Shingo Ota, Keisuke Satogami, Yuichi Ozaki and 8 more

Abstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Recent highlights from theInternational journal of cardiology. Heart & vasculature · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Teruaki WadaDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Yasutsugu ShionoDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Kentaro HondaDepartment of Thoracic and Cardiovascular Surgery, Wakayama Medical University, Wakayama, Japan.
Daisuke HigashiokaDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Akira TaruyaDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Masahiro TakahataDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Suwako FujitaDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Shingo OtaDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Keisuke SatogamiDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Yuichi OzakiDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Manabu KashiwagiDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Akio KuroiDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Takashi YamanoDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Kazushi TakemotoDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Takashi TanimotoDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Hironori KitabataDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Yoshiharu NishimuraDepartment of Thoracic and Cardiovascular Surgery, Wakayama Medical University, Wakayama, Japan.
Atsushi TanakaDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Impaired coronary flow reserve (CFR) portends a poor prognosis in patients with aortic stenosis. The present study aims to investigate how CFR changes over one year after transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis, and to explore factors related to the changes. Methods: Consecutive patients undergoing TAVI were registered. CFR in the left anterior descending artery was measured by transthoracic echocardiography on three occasions pre-TAVI, one-day post-TAVI, and one-year post-TAVI. Results: A total of 59 patients were enrolled, 46 of whom completed one-year follow-up. CFR was impaired in 35 (59.3%) patients pre-TAVI, but the impairment was only seen in 2 patients (4%) one-year post-TAVI. CFR value improved from 1.75 (1.50-2.10) cm/s pre-TAVI, to 2.00 (1.70-2.30) one-day post-TAVI, and further to 2.60 (2.30-3.10) one-year post-TAVI ( Conclusions: CFR is impaired in a considerable proportion of patients with severe aortic stenosis, but improvement is seen immediately after TAVI, and one year later. Patients with significant improvement of CFR had larger aortic valve area and greater increase in left ventricular ejection fraction after TAVI.

Indexed as

Aortic stenosisAS, aortic stenosisAVA, aortic valve areaAV-PG, aortic valve pressure gradientAVR, aortic valve replacementCFR, coronary flow reserveCoronary flow reserveLAD, left anterior descending coronary arteryLAVI, left atrial volume indexLVEF, left ventricular ejection fractionLV, left ventricleLVMI, left ventricular mass indexSAVR, surgical aortic valve replacementTAVI, transcatheter aortic valve implantationTranscatheter aortic valve implantation

Identifiers

PMID35873862
PMCPMC9304717

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.