ReviewFrontiers in neurology2022
Retained Primitive Reflexes and Potential for Intervention in Autistic Spectrum Disorders.
Review in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Intra- and Inter-Rater Reliability of Primitive Reflex Assessments in Youth Football Athletes.Journal of functional morphology and kinesiology · 2026Article
- Article
- Relationship of the Persistent Primitive Reflexes to Emotional and Behavioral Problems in Autistic and Typically Developing Children.Journal of autism and developmental disorders · 2026Article
- Factor Analysis of the Neurological Evaluation Scale (NES) and Corresponding Brain Function and Structures.International journal of methods in psychiatric research · 2026Article
- Retained primitive reflexes are independently associated with impaired postural control in adolescents with idiopathic scoliosis.Frontiers in neurology · 2026Article
- Developmental Disturbances in Animal Models of Autism Spectrum Disorder.Developmental neurobiology · 2025Review
- Evaluating Primitive Reflexes in Early Childhood as a Potential Biomarker for Developmental Disabilities.Journal of paediatrics and child health · 2025Review
- Cerebral Palsy Link to Sensorimotor System, Cognition, Emotion and Nociplastic Pain.Children (Basel, Switzerland) · 2025Review
- Detailed Analysis of the Palmomental Reflex and Its Clinical Significance.Brain and behavior · 2024Review
- The Assessment of Postural-Motor, Coordination, and Reflex Functions in Children and Adolescents with a History of Premature Verticalization and Ontogeny Disorders in Their First Year of Life.Children (Basel, Switzerland) · 2024Article
- Persistence of primitive reflexes associated with asymmetries in fixation and ocular motility values.Journal of eye movement research · 2024Article
- Identification and reduction of retained primitive reflexes by sensory stimulation in autism spectrum disorder: effects on qEEG networks and cognitive functions.BMJ case reports · 2023Article
- The Relationship between Retained Primitive Reflexes and Hemispheric Connectivity in Autism Spectrum Disorders.Brain sciences · 2023Article
- Attention deficit hyperactivity disorder is associated with (a)symmetric tonic neck primitive reflexes: a systematic review and meta-analysis.Frontiers in psychiatry · 2023Review
- The Inverted U: Exploring the Interconnectedness of Movement and Cognitive Function Across the Lifespan.Wiley interdisciplinary reviews. Cognitive scienceReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We provide evidence to support the contention that many aspects of Autistic Spectrum Disorder (ASD) are related to interregional brain functional disconnectivity associated with maturational delays in the development of brain networks. We think a delay in brain maturation in some networks may result in an increase in cortical maturation and development in other networks, leading to a developmental asynchrony and an unevenness of functional skills and symptoms. The paper supports the close relationship between retained primitive reflexes and cognitive and motor function in general and in ASD in particular provided to indicate that the inhibition of RPRs can effect positive change in ASD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.