Evidence map›Paper›PMID 35873644›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-

Hui Ma, Xingwu Duan, Runtian Zhang, Hang Li, Yang Guo, Ye Tian, Min Huang, Guangshan Chen, Zi Wang, Lingling Li

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Loureirin A is a narrow-spectrum antimicrobial agent againstAntimicrobial agents and chemotherapy · 2024
    Article
  5. Pharmacotherapy for Keloids and Hypertrophic Scars.International journal of molecular sciences · 2024
    Review
  6. Review
  7. Retracted: Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-Evidence-based complementary and alternative medicine : eCAM · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hui MaDepartment of Dermatology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, 23 Back Street, Art Museum, Dongcheng District, Beijing 100010, China.
Xingwu DuanDepartment of Dermatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 5 Shipping Warehouse, Dongcheng District, Beijing 100700, China.
Runtian ZhangDepartment of Dermatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 5 Shipping Warehouse, Dongcheng District, Beijing 100700, China.
Hang LiDepartment of Dermatology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.
Yang GuoDepartment of Dermatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 5 Shipping Warehouse, Dongcheng District, Beijing 100700, China.
Ye TianDepartment of Dermatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 5 Shipping Warehouse, Dongcheng District, Beijing 100700, China.
Min HuangDepartment of Dermatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 5 Shipping Warehouse, Dongcheng District, Beijing 100700, China.
Guangshan ChenDepartment of Dermatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 5 Shipping Warehouse, Dongcheng District, Beijing 100700, China.
Zi WangDepartment of Dermatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 5 Shipping Warehouse, Dongcheng District, Beijing 100700, China.
Lingling LiDepartment of Dermatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 5 Shipping Warehouse, Dongcheng District, Beijing 100700, China.ORCID https://orcid.org/0000-0002-4074-3007
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNCapital Medical University · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been recently shown that loureirin A (LA), a major active component of resina draconis, might be effective in the prevention and treatment of liver fibrosis. We examined whether LA could inhibit the formation of keloids. To investigate the pharmacological effects of loureirin A on keloid formation and the underlying mechanisms. CellTiter-Blue viability assays were used to examine the proliferation of keloid fibroblasts (KFs) that were treated with LA. Fibroblast migration was evaluated using a cell migration assay. Immunofluorescence staining was used to measure the expression of

Identifiers

PMID35873644
PMCPMC9307331
OpenAlexW4285592047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.