ArticleIndian journal of clinical biochemistry : IJCB2022
Direct Relationship Between Uric Acid and C-Reactive Protein and Its Implication in the Chronic Kidney Disease.
Article in Indian journal of clinical biochemistry : IJCB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 4 citations in OpenAlex.
- Association between cumulative changes of the C-reactive protein-triglyceride glucose index and the incidence of rapid kidney function decline: a nationwide prospective cohort study.Frontiers in nutrition · 2026Article
- The decreased serum levels of interleukin-38 in patients with gout and its clinical significance.Frontiers in immunology · 2024Article
- Study on the correlation between mineral bone metabolism and CRP in patients with SHPT during perioperative period.Immunity, inflammation and disease · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
Chronic Kidney disease (CKD) is a serious life threatening disease associated with morbidity and mortality in India. Hypothetical relationship between serum uric acid and C-Reactive protein (CRP) levels has been demonstrated in the pathophysiology of CKD. Fifty chronic kidney disease patients before dialysis and fifty controls were executed for measurement of serum uric acid and C-Reactive protein as well as other biochemical parameters analysis. Serum C-Reactive protein was measured by quantitative turbidimetric immunoassay. In this study, serum uric acid, creatinine, urea and C-Reactive protein levels were significant raised in CKD group to that of controls. Notably serum C-Reactive protein levels were significantly higher in the CKD patients associated with non-diabetic factors in comparison to diabetic associated CKD patients. A receiver operating characteristic curve (ROC) exhibited a strong association between uric acid and C-Reactive protein levels. A strong direct relationship between serum uric acid and C-Reactive protein in CKD patients are plausibly culprits in the progression of diseases.
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