Evidence map›Paper›PMID 35873589›Full record

ArticleFrontiers in pharmacology2022

Pharmacokinetic Differences of Wuji Pill Components in Normal and Chronic Visceral Hypersensitivity Irritable Bowel Syndrome Rats Attributable to Changes in Tight Junction and Transporters.

Zipeng Gong, Qing Yang, Yajie Wang, Xiaogang Weng, Yujie Li, Yu Dong, Xiaoxin Zhu, Ying Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Decoding Barberry Root's Therapeutic Network: A Synergistic Solution for IBS-D.Combinatorial chemistry & high throughput screening · 2026
    Article
  2. Wuji Pill andFrontiers in microbiology · 2026
    Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zipeng GongState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, China.
Qing YangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Yajie WangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Xiaogang WengInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Yujie LiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Yu DongGuang'An Men Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xiaoxin ZhuInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Ying ChenInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNGuiyang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Wuji pill, also called Wuji Wan (WJW), is an effective traditional medicine for the clinical treatment of irritable bowel syndrome (IBS). It is principally composed of

Indexed as

irritable bowel syndromepharmacokinetic differencestight junctiontransportersWuji pill

Identifiers

PMID35873589
PMCPMC9305487
OpenAlexW4284880611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.