Evidence map›Paper›PMID 35873453›Full record

ArticleChild development perspectives2022

Developmental costs associated with early maternal withdrawal.

Karlen Lyons-Ruth, Heather A Yarger

Abstract read
In one paragraph

Article in Child development perspectives, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Is neglect the first form of threat?Attachment & human development · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Karlen Lyons-RuthHarvard Medical School Cambridge Massachusetts USA.
Heather A YargerUniversity of Maryland College Park Maryland USA.ORCID https://orcid.org/0000-0001-8031-0700

Funding

HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
Neurobiology of Mothering and Infant StressR01HD079484 · NICHD · MCLEAN HOSPITAL · PI BOSQUET ENLOW, MICHELLE A, GRANT, PATRICIA ELLEN · 2015 to 2019
$3.6M
Psychopathology and Controlling Behavior in Adolescents.R01MH062030 · NIMH · CAMBRIDGE HEALTH ALLIANCE · PI LYONS-RUTH, KARLEN · 2001 to 2004
$946k
NCRR NIH HHS UL1 RR025758NICHD NIH HHS R01 HD079484NIMH NIH HHS R01 MH062030
6 · The paper itself

Abstract

Neglect is the most prevalent form of maltreatment, but it has been understudied relative to abuse. Additionally, developmental outcomes associated with early maternal withdrawal have been understudied relative to outcomes associated with harsh treatment. However, a large body of studies on rodents has documented the causal effect of low maternal care on altered stress responses in offspring. Other evidence from human studies links early maternal withdrawal to clinical levels of neglect. Studies of both rodents and humans suggest that, rather than the aversive responses (e.g., fight, flight, freeze) modeled in relation to threat of attack or harsh treatment, early maternal withdrawal is associated with increased calling and contact seeking to mothers. Moreover, two longitudinal studies indicate that early maternal withdrawal, but not negative-intrusive interaction, contributes to adolescent borderline psychopathology. The field needs prospective studies with well-operationalized constructs of maternal withdrawal to delineate the distinct developmental pathways that may be associated with neglect.

Indexed as

deprivationlow maternal nurturancematernal withdrawalneglectthreat

Identifiers

PMID35873453
PMCPMC9303254

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.