Evidence map›Paper›PMID 35873439›Full record

ArticleFrontiers in nutrition2022

The Effect of Green Tea as an Adjuvant to Enzyme Replacement Therapy on Oxidative Stress in Fabry Disease: A Pilot Study.

Giovanni Bertoldi, Gianni Carraro, Verdiana Ravarotto, Valentina Di Vico, Paola Baldini Anastasio, Nicola Vitturi, Francesco Francini, Lucia Federica Stefanelli, Lorenzo A Calò

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Fabry Disease: A Focus on the Role of Oxidative Stress.Antioxidants (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. The RAAS Goodfellas in Cardiovascular System.Journal of clinical medicine · 2023
    Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Giovanni BertoldiNephrology, Dialysis and Transplantation Unit, Department of Medicine, University of Padova, Padua, Italy.
Gianni CarraroNephrology, Dialysis and Transplantation Unit, Department of Medicine, University of Padova, Padua, Italy.
Verdiana RavarottoNephrology, Dialysis and Transplantation Unit, Department of Medicine, University of Padova, Padua, Italy.
Valentina Di VicoNephrology, Dialysis and Transplantation Unit, Department of Medicine, University of Padova, Padua, Italy.
Paola Baldini AnastasioNephrology, Dialysis and Transplantation Unit, Department of Medicine, University of Padova, Padua, Italy.
Nicola VitturiMetabolic Diseases Unit, Department of Medicine, University of Padova, Padua, Italy.
Francesco FranciniClinical Nutrition Unit, Department of Medicine, University of Padova, Padua, Italy.
Lucia Federica StefanelliNephrology, Dialysis and Transplantation Unit, Department of Medicine, University of Padova, Padua, Italy.
Lorenzo A CalòNephrology, Dialysis and Transplantation Unit, Department of Medicine, University of Padova, Padua, Italy.
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enzymatic replacement therapy (ERT) is not very effective in halting the progression of Fabry disease (FD) toward cardiovascular (CV)-renal remodeling, particularly in case of late diagnosis. FD patients have increased oxidative stress (OS), critical for the induction of CV-renal remodeling. We investigated the effects of an adjuvant antioxidant treatment to ERT on OS and the possible advantages for related complications. OS was evaluated in 10 patients with FD before ERT, after 12 months of ERT, and after 6 months of adjuvant green tea (GT) to ERT by the following experiments: expression of p22

Indexed as

enzyme replacement therapy (ERT)epigallocatechin-3-gallate (EGCG)fabry diseasegreen teaoxidative stress

Identifiers

PMID35873439
PMCPMC9304972
OpenAlexW4284878663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.