SynthesisFrontiers in nutrition2022
A Meta-Analysis on Vitamin D Supplementation and Asthma Treatment.
Synthesis in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Pooled it
- Efficacy and safety of vitamin D in the treatment of asthma: an overview of systematic reviews and meta-analyses.Frontiers in medicine · 2026Pooled it
- The efficacy of vitamin D supplementation in the management of childhood asthma: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Vitamin D for the management of asthma.The Cochrane database of systematic reviews · 2023Pooled it
- An Observational Study of the Role of Adiponectin and Vitamin D in Pediatric Asthma and Obesity.Children (Basel, Switzerland) · 2026Article
- Development and internal validation of a multidimensional nomogram integrating PIV, LDH, and FeNO for predicting poor asthma control in school-aged children.Frontiers in pediatrics · 2026Article
- Exploring Oxygen Therapy as a Supporting Treatment for Asthma: Current Insights and Perspectives.International journal of molecular sciences · 2025Review
- The therapeutic potential of vitamin D supplementation in asthma.Pharmacological reports : PR · 2025Review
- Identification of Priority Nutrients in the US: Targeting Malnutrition to Address Diet-Related Disease Across the Lifespan.Nutrients · 2025Article
- Vitamin D exerts endogenous control over TiScience · 2025Article
- Vitamin D deficiency and asthma morbidity in school-age children: a single-center cohort study.Frontiers in public health · 2025Article
- Gender Differences in the Interplay between Vitamin D and Microbiota in Allergic and Autoimmune Diseases.Biomedicines · 2024Review
- Low CD46 expression on activated CD4Frontiers in allergy · 2024Article
- Effect of Obesity on Lung Function in the Pediatric and Adult Populations with Asthma: A Review.Journal of clinical medicine · 2023Review
- Effect of baseline serum vitamin D level on symptom and medication scores of subcutaneous immunotherapy in children with mite allergy.Frontiers in pediatrics · 2022Article
- Progress in diagnosis and treatment of difficult-to-treat asthma in children.Therapeutic advances in respiratory diseaseReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Vitamin D, as an immunomodulator, may be related to the therapeutic effect of asthma patients, but the research in this area is still controversial. The aim of this meta-analysis was to analyze the role of vitamin D supplementation in the treatment of asthma patients. Materials and Methods: Randomized Controlled Trials (RCTs) of vitamin D supplementation in asthma were searched in PubMed, EMBASE, and the Cochrane library. Primary outcomes were forced expiratory volume in one second (FEV1), asthma exacerbations, Asthma Control Test scores (ACT scores), and fractional exhaled nitric oxide (FENO). Results: A total of 10 RCTs were included, including 1,349 patients. Vitamin D supplementation didn't affect the ACT scores (SMD = 0.04, 95% CI = -0.13 to 0.21, Conclusion: Vitamin D supplementation can reduce asthma exacerbations, especially in children, and within 6 months of follow up time. In addition, vitamin D has a positive effect on improving FEV1 of patients whose FEV1 baseline value is less than 70%, but more RCTs are still needed to support this conclusion. Systematic Review Registration: [https://inplasy.com], identifier [10.37766/inplasy20 22.6.0049].
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.