ReviewFrontiers in cellular and infection microbiology2022
Acaricides Resistance in Ticks: Selection, Diagnosis, Mechanisms, and Mitigation.
Review in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 2 syntheses or guidelines pooled it, 139 citations in OpenAlex.
- A systematic review of the effectiveness and utility of Lyme disease prevention measures in Canada, the United States, and Europe.BMC infectious diseases · 2025Pooled it
- Exploring the landscape of Babesia bovis vaccines: progress, challenges, and opportunities.Parasites & vectors · 2023Pooled it
- Comprehensive evaluation of tick infestation dynamics and host response in Kankrej and Holstein Friesian crossbred cattle.Veterinary and animal science · 2026Article
- Effects ofPathogens (Basel, Switzerland) · 2026Article
- mGem: A tale as old as blood-do tick-borne pathogens exploit arthropod antioxidant defenses?mBio · 2026Review
- Synergistic action of piperonyl butoxide with macrocyclic lactones in Rhipicephalus microplus.Experimental & applied acarology · 2026Article
- Acaricidal Activity of Liquid Culture Filtrates from Nematophagous Fungi AgainstPathogens (Basel, Switzerland) · 2026Article
- Acaricidal Activity and Transcriptional Modulation Induced by Randia aculeata Seed Extract in Rhipicephalus microplus.Acta parasitologica · 2026Article
- Rickettsia massiliae and its public health significance across Palearctic and Oriental regions: a scoping review.Infectious diseases of poverty · 2026Article
- Epidemiology and predilection-site distribution of tick infestation in communal cattle systems of Limpopo Province, South Africa.BMC veterinary research · 2026Article
- Efficacy of Purified Borrelial Lipoproteins (PBL) as an oral formulation in reducing transmission of Lyme spirochetes from reservoir hosts tobioRxiv : the preprint server for biology · 2026Article
- Assessing the susceptibility of 200 Rhipicephalus microplus populations to fluralaner using larval immersion test: A nationwide analysis from Brazil.Parasites & vectors · 2026Article
- Acaricidal Effect of Essential Oils in the Control ofPathogens (Basel, Switzerland) · 2026Article
- Ticks and tick-borne diseases: A call for comprehensive tick surveillance in India under One Health approach.The Indian journal of medical research · 2026Review
- Acaricide resistance among single-host and multi-host ticks in sub-Saharan Africa: Current status, drivers, and control strategies.Veterinary world · 2026Review
- Comprehensive validation of the rapid tick exposure test (RaTexT®): accuracy, reproducibility and comparative performance to detect acaricide resistance in livestock ticks.Parasites & vectors · 2026Article
- Cattle Immunization with T7 Phage-Displayed Whole-Tick Antigens ReducesPathogens (Basel, Switzerland) · 2026Article
- A natural barrier: tick-repellent potential of a spruce-derived volatile blend against Hyalomma excavatum and Ixodes ricinus.Pest management science · 2026Article
- Microbiota-immune crosstalk in livestock: implications for tick-borne disease control.Frontiers in immunology · 2026Review
- Management, socioeconomics, and One Health determinants of tick infestation in communal cattle production systems of South Africa.Frontiers in veterinary science · 2026Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ticks are blood-feeding ecto-parasites that have a cosmopolitan distribution in tropical and subtropical regions of the world. Ticks cause economic losses in the form of reduced blood, meat and dairy products, as well as pathogen transmission. Different acaricides such as organochlorines, organophosphates, formamidines (e.g. amitraz), synthetic pyrethroids, macrocyclic lactones, fipronil, and fluazuron are currently used sequentially or simultaneously to control tick infestations. Most acaricide treatments now face increasingly high chances of failure, due to the resistance selection in different tick populations against these drugs. Acaricide resistance in ticks can be developed in different ways, including amino acid substitutions that result in morphological changes in the acaricide target, metabolic detoxification, and reduced acaricide entry through the outer layer of the tick body. The current literature brings a plethora of information regarding the use of different acaricides for tick control, resistance selection, analysis of mutations in target sites, and resistance mitigation. Alternatives such as synergistic use of different acaricides, plant-derived phytochemicals, fungi as biological control agents, and anti-tick vaccines have been recommended to avoid and mitigate acaricide resistance. The purpose of this review was to summarize and discuss different acaricides applied for tick control, their mechanisms of action and resistance selection, genetic polymorphisms in their target molecules, as well as the approaches used for diagnosis and mitigation of acaricide resistance, specifically in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.