Evidence map›Paper›PMID 35872981›Full record

ReviewFrontiers in endocrinology2022

Target Therapy in Thyroid Cancer: Current Challenge in Clinical Use of Tyrosine Kinase Inhibitors and Management of Side Effects.

Ivana Puliafito, Francesca Esposito, Angela Prestifilippo, Stefania Marchisotta, Dorotea Sciacca, Maria Paola Vitale, Dario Giuffrida

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Neutrophil-To-Lymphocyte Ratio as a Prognostic Indicator in Thyroid Cancer.Cancer control : journal of the Moffitt Cancer Center
    Pooled it
  2. Review
  3. Article
  4. Evolving trends in pediatric thyroid nodules and cancer management.Annals of pediatric endocrinology & metabolism · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Role of [Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
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  17. Review
  18. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ivana PuliafitoMedical Oncology Unit, Istituto Oncologico del Mediterraneo SpA, Viagrande, Italy.
Francesca EspositoIOM Ricerca Srl, Viagrande, Italy.
Angela PrestifilippoMedical Oncology Unit, Istituto Oncologico del Mediterraneo SpA, Viagrande, Italy.
Stefania MarchisottaInternal Medicine Unit, Giuseppe Giglio Foundation, Cefalù, Italy.
Dorotea SciaccaMedical Oncology Unit, Istituto Oncologico del Mediterraneo SpA, Viagrande, Italy.
Maria Paola VitaleHospital Pharmacy Unit, Istituto Oncologico del Mediterraneo SpA, Viagrande, Italy.
Dario GiuffridaMedical Oncology Unit, Istituto Oncologico del Mediterraneo SpA, Viagrande, Italy.
Fondazione Istituto G. Giglio di Cefalù · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid cancer (TC) is the most common endocrine malignancy. TC is classified as differentiated TC (DTC), which includes papillary and follicular subtypes and Hürthle cell variants, medullary TC (MTC), anaplastic TC (ATC), and poorly differentiated TC (PDTC). The standard of care in DTC consists of surgery together with radioactive iodine (

Indexed as

Carcinoma, NeuroendocrineThyroid Carcinoma, AnaplasticThyroid NeoplasmsHumansIodine RadioisotopesProtein Kinase InhibitorsIodine RadioisotopesProtein Kinase Inhibitorsadverse eventsmultikinase inhibitorstarget therapythyroid cancertyrosine kinase inhibitors

Identifiers

PMID35872981
PMCPMC9304687
OpenAlexW4284899571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.