Evidence map›Paper›PMID 35872883›Full record

ArticleFrontiers in cardiovascular medicine2022

Performance of PRECISE-DAPT and Age-Bleeding-Organ Dysfunction Score for Predicting Bleeding Complication During Dual Antiplatelet Therapy in Chinese Elderly Patients.

Liang Dong, Cao Lu, Chen Wensen, Chen Fuzhong, Muhammad Khalid, Dong Xiaoyu, Li Guangjuan, Qian Yanxia, Zhang Yufeng, Liu Xinjian and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Liang DongDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Cao LuDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Chen WensenOffice of Infection Management, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Chen FuzhongDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Muhammad KhalidDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Dong XiaoyuDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Li GuangjuanDepartment of Cardiology, Xinjiang Yili Friendship Hospital, Yili Kazak Autonomous Prefecture, Xinjiang, China.
Qian YanxiaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zhang YufengDepartment of Cardiology, Xinjiang Yili Friendship Hospital, Yili Kazak Autonomous Prefecture, Xinjiang, China.
Liu XinjianDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Chen LeileiDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wang JunhongDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNJiangsu Province Hospital · CNYili Friendship Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recently, the Age-Bleeding-Organ Dysfunction (ABO) algorithm was recommended by the Asian Pacific Society of Cardiology Consensus as a binary approach to evaluate bleeding risk. This analysis made comparison of the predictive performances between the PRECISE-DAPT and ABO bleeding score in identifying the risk of 12-months major bleeding in Chinese elderly patients over 65 years old patients who underwent percutaneous coronary intervention (PCI) during dual-antiplatelet therapy period. Methods: A total of 2,037 elderly coronary artery disease (CAD) patients (≥65 years) receiving dual antiplatelet therapy (DAPT) after PCI were enrolled in the study. The predictive accuracy of the two bleeding risk scores (PRECISE-DAPT and ABO) was compared for identifying the risk of bleeding during the dual-antiplatelet therapy in patients who underwent PCI. Major clinically relevant bleeding events were defined according to the Bleeding Academic Research Consortium (BARC) criteria. Results: The PRECISE-DAPT score in the no bleeding, BARC = 1 bleeding, BARC ≥ 2 bleeding patients was 23.55 ± 10.46, 23.23 ± 10.03, and 33.54 ± 14.33 ( Conclusion: No matter of clinical presentation in Asian 65-years older patients with DAPT, the PRECISE-DAPT, and ABO scores had the similar discriminative ability for 12-months BARC ≥ 2 bleeding. Considering the simplicity and reliability, the PRECISE-DAPT score might be more clinically applicable in the overall population and ACS patients in bleeding prediction.

Indexed as

ABO scorebleeding risk scoresdual-antiplatelet therapypercutaneous coronary interventionPRECISE-DAPT

Identifiers

PMID35872883
PMCPMC9304588
OpenAlexW4284899563

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.