Evidence map›Paper›PMID 35872865›Full record

ArticleBioMed research international2022

Apoptotic and Antioxidant Activity of Gold Nanoparticles Synthesized Using Marine Brown Seaweed: An In Vitro Study.

S Rajeshkumar, R P Parameswari, J Jayapriya, M Tharani, Huma Ali, Nada H Aljarba, Saad Alkahtani, Saud Alarifi

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

S RajeshkumarCenter for Transdisciplinary Research (CFTR), Nanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, India.ORCID https://orcid.org/0000-0001-7059-8894
R P ParameswariCenter for Transdisciplinary Research (CFTR), Nanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, India.ORCID https://orcid.org/0000-0003-3167-2873
J JayapriyaCenter for Transdisciplinary Research (CFTR), Nanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, India.
M TharaniCenter for Transdisciplinary Research (CFTR), Nanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, India.
Huma AliDepartment of Chemistry, Maulana Azad National Institute of Technology, Bhopal, India.
Nada H AljarbaDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, P. O. Box 84428, Riyadh 11671, Saudi Arabia.
Saad AlkahtaniDepartment of Zoology, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia.
Saud AlarifiDepartment of Zoology, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia.
Saveetha University · INKing Saud University · SAMaulana Azad National Institute of Technology · INPrincess Nourah bint Abdulrahman University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A major paradigm shift in the field of nanobiotechnology is the invention of an eco-friendly, economical, and green approach for synthesis of metal nanoparticles. In the present study, we have synthesized gold nanoparticles (AuNPs) using aqueous extracts of marine brown seaweed Sargassum longifolium. The synthesized nanoparticle was subjected to characterization using different techniques such as UV-Vis spectroscopy, Fourier transform infrared spectroscopy, atomic force microscope, scanning electron microscope, transmission electron microscope, and elemental dispersive X-ray diffraction. Further, the seaweed extract and the synthesized AuNPs were evaluated for its anticancer effect using MG-63 human osteosarcoma cells besides in vitro antioxidant effect. The formation of S. longifolium-mediated synthesis of gold nanoparticles was demonstrated by UV-Vis spectroscopy. Presence of elemental gold was confirmed by EDX analysis. TEM analysis demonstrated spherical morphology of the synthesized AuNPs and SEM analysis revealed the particle size to be in the range of 10-60 nm. The FTIR showed the presence of hydroxyl functional groups. The toxicity of S. longifolium extract and the synthesized AuNPs was tested using brine shrimp lethality assay at different concentrations with results showing both seaweed extract and AuNPs to be nontoxic. Both S. longifolium and AuNPs exhibited significant antioxidant activity by scavenging DPPH free radicals and H

Indexed as

AntioxidantsGoldMetal NanoparticlesOsteosarcomaSeaweedGreen Chemistry TechnologyHumansHydrogen PeroxidePlant ExtractsSpectroscopy, Fourier Transform InfraredAntioxidantsGoldHydrogen PeroxidePlant Extracts

Identifiers

PMID35872865
PMCPMC9300303
OpenAlexW4285392793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.