Evidence map›Paper›PMID 35872863›Full record

ArticleBioMed research international2022

Vitamin D Protects against Traumatic Brain Injury via Modulating TLR4/MyD88/NF-

Hongsheng Jiang, Xinyu Yang, Yanzhou Wang, Caifeng Zhou

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 26 citations in OpenAlex.

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  14. Vitamin D deficiency promotes intracranial aneurysm rupture.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hongsheng JiangDepartment of Neurosurgery, Cangzhou Central Hospital, Cangzhou, China.ORCID https://orcid.org/0000-0002-4212-4269
Xinyu YangDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.ORCID https://orcid.org/0000-0002-2194-4137
Yanzhou WangDepartment of Neurosurgery, Cangzhou Central Hospital, Cangzhou, China.ORCID https://orcid.org/0000-0003-0223-0347
Caifeng ZhouDepartment of Neurosurgery, Cangzhou Central Hospital, Cangzhou, China.ORCID https://orcid.org/0000-0001-9708-8026
Cangzhou Central Hospital · CNTianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D (VD) deficiency is associated with neuroinflammation and neurocognitive deficits in patients with traumatic brain injury (TBI). The present study was aimed at investigating the therapeutic effects of VD and the molecular mechanisms after TBI. After the intraperitoneal injection of VD (1

Indexed as

Brain EdemaBrain Injuries, TraumaticAnimalsDisease Models, AnimalMicrogliaMyeloid Differentiation Factor 88Neuroinflammatory DiseasesNF-kappa BRatsSignal TransductionToll-Like Receptor 4Vitamin DMyd88 protein, ratMyeloid Differentiation Factor 88NF-kappa BTlr4 protein, ratToll-Like Receptor 4Vitamin D

Identifiers

PMID35872863
PMCPMC9307360
OpenAlexW4285594040

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.