SynthesisFrontiers in medicine2022
Acute Ankle Sprain Management: An Umbrella Review of Systematic Reviews.
Synthesis in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mild Ankle Sprain Treatment: Functional Bandaging vs. no Immobilization. Clinical Trial, Randomized, in Pediatric Population
Multicentre, Randomized, Clinical Trial in Children With Mild Ankle Sprain: Bandaging vs. no Immobilization
Therapeutic Low Laser Therapy and Kinesio Taping in Patients With Grade 1 and Grade 2 Lateral Ankle Sprain
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Is Kinesio taping an effective approach for acute ankle sprains? A systematic review and meta-analysis.EFORT open reviews · 2026Pooled it
- Physical therapy versus conventional treatment for grade I and II acute ankle sprains: trial sequential analysis and meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Pooled it
- Heel kicking exercise rapidly improves pain and function in patients with acute lateral ankle sprain: a randomized controlled trial.BMC musculoskeletal disorders · 2025Trial
- Randomized controlled trial study of intelligent rehabilitation training system for functional ankle instability.Scientific reports · 2024Trial
- Trial
- Ankle pump exercises do not produce clinically meaningful benefits in oedema, pain, functionality or mobility after acute ankle sprain: a randomised controlled trial.Brazilian journal of physical therapy · 2026Article
- Article
- PRICE (Protection, Rest, Ice, Compression, Elevation) vs. PEACE and LOVE (Protection, Elevation, Avoid anti-inflammatories, Compression, Education and Load, Optimism, Vascularization, Exercise) in adolescent lateral ankle sprain rehabilitation: a randomized prospective comparative study of muscle strength and dynamic balance.BMC sports science, medicine & rehabilitation · 2026Article
- Fu's subcutaneous needling versus bracing combined with exercise therapy in the treatment of postacute lateral ankle sprain and the prevention of chronic ankle instability: a randomized controlled trial protocol.Journal of orthopaedic surgery and research · 2026Article
- The effects of pulsed electromagnetic field therapy on pain and physical functions in patients with soft tissue injuries: a systematic review of randomised controlled trials.Frontiers in sports and active living · 2026Review
- Functional outcomes and rehabilitation behaviors following ankle sprain in amateur padel players: a cross-sectional study.Frontiers in medicine · 2026Article
- Platelet-rich plasma and hyaluronic acid in the treatment of acute ankle sprains: A review.Biomolecules & biomedicine · 2025Review
- Assessment of information quality and reliability on ankle sprains in short videos from Douyin and Bilibili.Scientific reports · 2025Article
- Efficacy of Autologous Platelet-Rich Plasma for the Treatment of Ankle Sprain: A Systematic Review of Literature with Limited Meta-Analysis.Indian journal of orthopaedics · 2025Review
- Factors Associated with Driving Ability and Changes After Immobilization of the Right Lower Limb: A Driving Simulator Study.Journal of clinical medicine · 2025Article
- Non-restraint in pediatric ankle sprain: a non-inferiority randomized clinical trial.European journal of pediatrics · 2024Article
- Topical Treatment Is Effective and Safe for Acute Ankle Sprains: The Multi-Center Double-Blind Randomized Placebo-Controlled TRAUMED Trial.Journal of clinical medicine · 2024Article
- A Rehabilitation Algorithm After Lateral Ankle Sprains in Professional Football (Soccer): An Approach Based on Clinical Practice Guidelines.International journal of sports physical therapy · 2024Article
- Cryo plus Ultrasound Therapy, a Novel Rehabilitative Approach for Football Players with Acute Lateral Ankle Injury Sprain: A Pilot Randomized Controlled Trial.Sports (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Even though ankle sprains are among the most frequent musculoskeletal injuries seen in emergency departments, management of these injuries continues to lack standardization. Our objective was to carry out an umbrella review of systematic reviews to collect the most effective evidence-based treatments and to point out the state-of-the-art management for this injury. PubMed, Scopus, Web of Science, and the Cochrane library were searched from January 2000 to September 2020. After removing duplicates and applying the eligibility criteria, based on titles and abstracts, 32 studies were screened. At the end of the process, 24 articles were included in this umbrella review with a mean score of 7.7/11 on the AMSTAR quality assessment tool. We found evidence supporting the effectiveness of non-surgical treatment in managing acute ankle sprain; moreover, functional treatment seems to be preferable to immobilization. We also found evidence supporting the use of paracetamol or opioids as effective alternatives to non-steroidal anti-inflammatory drugs to reduce pain. Furthermore, we found evidence supporting the effectiveness of manipulative and supervised exercise therapy to prevent re-injury and restore ankle dorsiflexion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.