ArticleFrontiers in medicine2022
Impact of Air Pollution on the Ocular Surface and Tear Cytokine Levels: A Multicenter Prospective Cohort Study.
Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Impact of particulate matter and air pollution on ocular surface disease: A systematic review of preclinical and clinical evidence.The ocular surface · 2025Pooled it
- PM 2.5 suppresses IL-8-mediated epithelial migration of human conjunctival epithelial cells.Journal of the Chinese Medical Association : JCMA · 2026Article
- Interactions of Mucomimetic Polymers and Meibomian Surface Films upon Exposure to Environmental Stressors.Biomolecules · 2026Article
- Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects.Animal models and experimental medicine · 2026Review
- Environmental Drivers of Dry Eye Disease: A Narrative Review of Pollutants, Climate, and Indoor Exposures with Practice Recommendations.Ophthalmology and therapy · 2026Review
- The exposure-lag-response association between solar radiation components and meibomian gland dysfunction in Shanghai, China.Frontiers in public health · 2026Article
- Ambient air pollutants and outpatient visits for conjunctivitis in Hefei, China: a time-series study of hospital-based data during 2014-2023.Frontiers in public health · 2026Article
- Emerging mechanisms in dry eye disease: apoptosis-associated tear MicroRNAs and toxicant-related alterations of the glycocalyx and lipid rafts.Frontiers in ophthalmology · 2026Article
- Real-Life Assessment of Multi-Pollutant Exposure and Its Impact on the Ocular Surface: The Bike-Eye Pilot Study on Urban Cyclists in Bologna.International journal of environmental research and public health · 2025Article
- Microplastics identified in commercial over-the-counter lubricant eyedrops.Eye (London, England) · 2025Article
- Letter to the Editor Re: "Comparison of 20% Autologous Platelet-Rich Plasma Versus Conventional Treatment in Moderate to Severe Dry Eye Patients".Turkish journal of ophthalmology · 2025Article
- Circadian disruption and ROS-NLRP3 signaling mediate sleep deprivation-enhanced silica nanoparticle toxicity in lacrimal glands.Journal of nanobiotechnology · 2025Article
- Wildfire Smoke Induces Eye Surface Inflammation and Tear Film Changes in a Human Experimental Model.Translational vision science & technology · 2025Article
- Rebamipide Enhances Pathogen Defense and Mitigates Inflammation in a Particulate Matter-Induced Ocular Surface Inflammation Rat Model.International journal of molecular sciences · 2025Article
- Absorption of Toxicants from the Ocular Surface: Potential Applications in Toxicology.Biomedicines · 2025Review
- Influencing of coal industry related airborne particulate matter on ocular surface tear film injury and inflammatory factor expression in Sprague-Dawley rats.Open life sciences · 2025Article
- Oculomics meets exposomics: a roadmap for applying multi-modal ocular biomarkers in precision environmental health research.Exposome · 2025Review
- Microplastics and nanoplastics in the ocular environment: Pathways, toxic effects, and future challenges.Current research in toxicology · 2025Review
- Pathological Mechanisms of Particulate Matter-Mediated Ocular Disorders: A Review.International journal of molecular sciences · 2024Review
- Greater exposure to PMEnvironmental health : a global access science source · 2024Observational
Corrections and comments
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Authors and funding
13 authors at 10 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To assess air pollution-induced changes on ocular surface and tear cytokine levels. Methods: As a prospective multicenter cohort study, 387 dry eye disease (DED) participants were recruited from five provinces in China and underwent measurements of ocular surface disease index (OSDI), Schirmer's I test (ST), tear meniscus height (TMH), tear film break-up time (TBUT), corneal fluorescein staining (CFS), meibomian gland (MG) function, and tear cytokines. The associations between ocular surface parameters and exposure to particulate matter (PM), ozone (O Results: In the multi-pollutant model, the OSDI score was positively correlated with PM with diameter ≤2.5 μm (PM Conclusion: Increased PM
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.