Evidence map›Paper›PMID 35872085›Full record

ArticleRespiratory investigation2022

Patient-centered outcomes at hospital discharge in mechanically ventilated COVID-19 patients in Kobe, Japan: A single-center retrospective cohort study.

Jiro Ito, Daisuke Kawakami, Ryutaro Seo, Kentaro Iwata, Kenjiro Ouchi, Suguru Nonami, Yusuke Miyoshi, Masao Tatebe, Takahiro Tsuchida, Yoko Asaka and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Respiratory investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Jiro ItoDepartment of Anesthesia and Critical Care, Kobe City Medical Center General Hospital, Kobe, Japan. Electronic address: phyandeth69boo@gmail.com.
Daisuke KawakamiDepartment of Anesthesia and Critical Care, Kobe City Medical Center General Hospital, Kobe, Japan.
Ryutaro SeoDepartment of Emergency Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
Kentaro IwataDepartment of Rehabilitation, Kobe City Medical Center General Hospital, Kobe, Japan.
Kenjiro OuchiDepartment of Anesthesia and Critical Care, Kobe City Medical Center General Hospital, Kobe, Japan.
Suguru NonamiDepartment of Anesthesia and Critical Care, Kobe City Medical Center General Hospital, Kobe, Japan.
Yusuke MiyoshiDepartment of Anesthesia and Critical Care, Kobe City Medical Center General Hospital, Kobe, Japan.
Masao TatebeDepartment of Anesthesia and Critical Care, Kobe City Medical Center General Hospital, Kobe, Japan.
Takahiro TsuchidaDepartment of Anesthesia and Critical Care, Kobe City Medical Center General Hospital, Kobe, Japan.
Yoko AsakaDepartment of Emergency Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
Chikashi TakedaDepartment of Anesthesia, Kyoto University Hospital, Kyoto, Japan.
Hiromasa NishiharaDepartment of Rehabilitation, Kobe City Medical Center General Hospital, Kobe, Japan.
Hiroyuki MimaDepartment of Anesthesia and Critical Care, Kobe City Medical Center General Hospital, Kobe, Japan.
Asako DoiDepartment of Infectious Diseases, Kobe City Medical Center General Hospital, Kobe, Japan.
Keisuke TomiiDepartment of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
Koichi AriyoshiDepartment of Emergency Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
Kobe City Medical Center General Hospital · JPKyoto University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundApart from saving the lives of coronavirus disease (COVID-19) patients on mechanical ventilation (MV), recovery from the sequelae of prolonged MV (PMV) is an emerging issue.c

methodsWe conducted a retrospective study among consecutive adult COVID-19 patients admitted to an intensive care unit (ICU) in Kobe, Japan, between March 3, 2020, and January 31, 2021, and received invasive MV. Clinical outcomes included in-hospital mortality and recovery from COVID-19 in survivors regarding organ dysfunction, respiratory symptoms, and functional status at discharge. We compared survivors' outcomes with MV durations of >14 days and ≤14 days.

resultsWe included 85 patients with a median age of 69 years (interquartile range, 64-75 years); 76 (89%) patients had at least 1 comorbidity, 72 (85%) were non-frail, and 79 (93%) were functionally independent before COVID-19 infection. Eighteen patients (21%) died during hospitalization. At discharge, 59/67 survivors (88%) no longer required respiratory support, 50 (75%) complained of dyspnea, and 40 (60%) were functionally independent. Of the survivors, 23 patients receiving MV for >14 days had a worse recovery from COVID-19 at discharge compared with those on MV for ≤14 days, as observed using the Barthel index (median: 35 [5-65] vs. 100 [85-100]), ICU mobility scale (8 [5-9] vs. 10 [10-10]), and functional oral intake scale (3 [1-7] vs. 7 [7-7]) (P < 0.0001).

conclusionAlthough four-fifths of the patients survived and >50% of survivors demonstrated clinically important recovery in organ function and functional status during hospitalization, PMV was related to poor recovery from COVID-19 at discharge.

Indexed as

COVID-19Respiration, ArtificialAdultAgedCritical IllnessHospitalsHumansJapanMiddle AgedPatient-Centered CarePatient DischargeRetrospective StudiesActivities of daily livingCOVID-19Critical careJapanMechanical ventilation

Identifiers

PMID35872085
PMCPMC9271455
OpenAlexW4285008404

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.