SynthesisClinical oral investigations2022
Occlusion effects of bioactive glass and hydroxyapatite on dentinal tubules: a systematic review.
Synthesis in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Effectiveness of S-PRG-based varnish and bioactive glass-based air polishing in the management of dentin hypersensitivity and their effects on tooth color: a 12-month randomized clinical trial.BMC oral health · 2026Trial
- Effects of desensitizing treatments on acid-etched dentin: debris precipitation, bond strength and tag formation.Odontology · 2026Article
- Article
- Synthesis, characterization and evaluation of novel bleaching gels containing bioactive glass and nano-hydroxyapatite on hydrogen peroxide diffusion, bleaching efficacy and enamel protection.Clinical oral investigations · 2025Article
- In vitro study on the bacteriostatic effect of Amoxicillin-loaded Nano-hydroxyapatite and its capability in occluding dentinal tubules.Scientific reports · 2025Article
- Bioactive glass products for the treatment of dentin hypersensitivity: a scoping review.Clinical oral investigations · 2025Article
- Role of diode laser (810 nm) and/or fluoride varnish for the treatment of gamma-irradiated hypersensitive human dentin (An in vitro study).Scientific reports · 2025Article
- Harnessing strontium in regenerative dentistry: progress and perspectives.Frontiers in bioengineering and biotechnology · 2025Review
- Effects of Sr/F-bioactive glass nanoparticles on pH, elemental release, dentin remineralisation, and cytotoxicity of 1.1% NaF toothpaste.Biomaterial investigations in dentistry · 2025Article
- Effect of an experimental desensitizer with a hydroxyapatite-capsaicin composite applied before in-office dental bleaching on hydrogen peroxide diffusion, color and surface changes.Clinical oral investigations · 2024Article
- A Review on Enhancing the Life of Teeth by Toothpaste Containing Bioactive Glass Particles.Current oral health reports · 2024Review
- Triple Function of Amelogenin Peptide-Chitosan Hydrogel for Dentin Repair.Journal of dental research · 2023Article
- Synthesis and characterization of hydroxyapatite nanoparticles and their effects on remineralization of demineralized enamel in the presence of Er,Cr: YSGG laser irradiation.BMC oral health · 2023Article
- Nano-CT characterization of dentinal tubule occlusion in SDF-treated dentin.Scientific reports · 2023Article
- The Effect of Three Desensitizing Toothpastes on Dentinal Tubules Occlusion and on Dentin Hardness.Biomedicines · 2023Article
- Efficiency of Various Tubular Occlusion Agents in Human Dentin after In-Office Tooth Bleaching.Journal of functional biomaterials · 2023Article
- The Effectiveness of Calcium Phosphates in the Treatment of Dentinal Hypersensitivity: A Systematic Review.Bioengineering (Basel, Switzerland) · 2023Review
- Synthesis and characterization of nano bioactive glass for improving enamel remineralization ability of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP).BMC oral health · 2022Article
- Evaluation of dentinal tubule occlusion by Fluoridated and Non-fluoridated Bioactive Glass and Propolis desensitizers by scanning electron microscopy.Journal of oral biology and craniofacial researchArticle
- Comparative Study of Anti-COVID Mouthwash and Remineralization Agents on Dentinal Tubular Occlusion: AnJournal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveBioactive glass and hydroxyapatite are biocompatible materials used as an adjunct to various dental materials. The present study aimed to evaluate the occlusion effects of bioactive glasses and hydroxyapatite on dental tubules. MATERIALS AND
methodsWe searched the PubMed/Medline, Embase, and Web of Science databases for the relevant records. The methodological quality of the studies was assessed by an accepted quality assessment tool.
resultsFrom the electronic databases, 372 articles were retrieved. After evaluating the records, 35 in vitro studies were included. The studies revealed a low risk of bias. The primary outcomes from bioactive glass studies demonstrated the potential efficacy of both bioactive glass and hydroxyapatite in dentin tubule occlusion compared to the control.
conclusionThe current systematic review showed that bioactive glass and hydroxyapatite could effectively occlude the dentinal tubules. Thus, desensitizing agents containing bioactive glass and hydroxyapatite can be used to manage dentin hypersensitivity (DH). However, long-term follow-up clinical trials are required in the future before definitive recommendations can be made. CLINICAL RELEVANCE: This work achieved a satisfactorily systematic review for assessing desensitizing agents containing bioactive glass and hydroxyapatite in dentine hypersensitivity treatments recommended for clinical practice and research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.