Evidence map›Paper›PMID 35871593›Full record

ArticleInternal medicine (Tokyo, Japan)2023

A Woman with Rheumatoid Arthritis Who Successfully Delivered a Healthy Child with Continuous Administration of Sarilumab Throughout Pregnancy.

Satoshi Mizutani, Yuki Okunishi, Tatsuya Tamada, Hiroyuki Tanaka, Yuhei Ito, Yoshiki Yamamoto, Asa Kitamura, Hiroaki Tanaka, Tomoaki Ikeda, Ayako Nakajima

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Breast and Nipple Dermatoses During Lactation.The Australasian journal of dermatology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Satoshi MizutaniCenter for Rheumatic Diseases, Mie University Hospital, Japan.
Yuki OkunishiCenter for Rheumatic Diseases, Mie University Hospital, Japan.
Tatsuya TamadaCenter for Rheumatic Diseases, Mie University Hospital, Japan.
Hiroyuki TanakaCenter for Rheumatic Diseases, Mie University Hospital, Japan.
Yuhei ItoCenter for Rheumatic Diseases, Mie University Hospital, Japan.
Yoshiki YamamotoCenter for Rheumatic Diseases, Mie University Hospital, Japan.
Asa KitamuraDepartment of Obstetrics and Gynecology, Mie University Faculty of Medicine, Japan.
Hiroaki TanakaDepartment of Obstetrics and Gynecology, Mie University Faculty of Medicine, Japan.
Tomoaki IkedaDepartment of Obstetrics and Gynecology, Mie University Faculty of Medicine, Japan.
Ayako NakajimaCenter for Rheumatic Diseases, Mie University Hospital, Japan.
Mie University Hospital · JPMie University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a patient with rheumatoid arthritis (RA) who successfully delivered a healthy child with continuous administration of sarilumab throughout pregnancy. She delivered her first child, a healthy boy, following in vitro fertilization-embryo transfer (IVF-ET) while using etanercept and low-dose prednisolone. Disease activity persisted after delivery, so etanercept was switched to sarilumab. She became pregnant by IVF-ET again. Because RA was still active, sarilumab was continued during pregnancy. She delivered a healthy girl at the 38th week of gestation by Caesarean section. No abnormalities were detected at or within 6 months after birth. Sarilumab was safe and effective in this pregnant woman with RA.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidAntibodies, Monoclonal, HumanizedCesarean SectionChildEtanerceptFemaleHumansMalePregnancyAntibodies, Monoclonal, HumanizedAntirheumatic AgentsEtanerceptsarilumabassisted reproductive technologyinfertilityinterleukin-6 inhibitorpregnancyrheumatoid arthritissarilumab

Identifiers

PMID35871593
PMCPMC10017234
OpenAlexW4286543475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.