Evidence map›Paper›PMID 35871422›Full record

SynthesisAge and ageing2022

Association between multimorbidity and hospitalization in older adults: systematic review and meta-analysis.

Luciana Pereira Rodrigues, Andréa Toledo de Oliveira Rezende, Felipe Mendes Delpino, Carolina Rodrigues Mendonça, Matias Noll, Bruno Pereira Nunes, Cesar de Oliviera, Erika Aparecida Silveira

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Age and ageing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed, 7 pooled it
21.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 7 syntheses or guidelines pooled it, 152 citations in OpenAlex.

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45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Luciana Pereira RodriguesPostgraduate Program in Health Sciences, School of Medicine, Federal University of Goiás, Goiânia, Brazil.ORCID 0000-0002-6499-1451
Andréa Toledo de Oliveira RezendePostgraduate Program in Health Sciences, School of Medicine, Federal University of Goiás, Goiânia, Brazil.
Felipe Mendes DelpinoDepartment of Nursing in Public Health, Federal University of Pelotas, Pelotas, Brazil.
Carolina Rodrigues MendonçaPostgraduate Program in Health Sciences, School of Medicine, Federal University of Goiás, Goiânia, Brazil.
Matias NollPostgraduate Program in Health Sciences, School of Medicine, Federal University of Goiás, Goiânia, Brazil.
Bruno Pereira NunesPostgraduate Program in Nursing, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Cesar de OlivieraDepartment of Epidemiology & Public Health, Institute of Epidemiology & Health Care, University College London, London, UK.
Erika Aparecida SilveiraPostgraduate Program in Health Sciences, School of Medicine, Federal University of Goiás, Goiânia, Brazil.
Universidade Federal de Goiás · BRUniversidade Federal de Pelotas · BRUniversity College London · GBUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultimorbidity is defined as the presence of multiple chronic conditions in the same individual. Multimorbidity is more prevalent in older adults and can lead to several adverse health outcomes.

methodsWe systematically reviewed evidence from observational studies to verify the association between multimorbidity and hospitalization in older adults. Furthermore, we also aimed to identify whether it changes according to gender, advanced age, institutionalization, and wealth of the country of residence. We searched the PubMed, Embase and Scopus databases from December 2020 to April 2021. The analysed outcomes were as follows: hospitalization, length of stay and hospital readmission.

resultsOf the 6,948 studies identified in the databases, 33 were included in this review. From the meta-analysis results, it was found that multimorbidity, regardless of the country's wealth, was linked to hospitalization in older adults (OR = 2.52, CI 95% = 1.87-3.38). Both definitions of multimorbidity, ≥2 (OR = 2.35, 95% CI = 1.34-4.12) and ≥3 morbidities (OR = 2.52, 95% CI = 1.87-3.38), were associated with hospitalization. Regardless of gender, multimorbidity was associated with hospitalization (OR = 1.98, 95% CI = 1.67-2.34) and with readmission (OR = 1.07, 95% CI = 1.04-1.09). However, it was not possible to verify the association between multimorbidity and length of stay.

conclusionsMultimorbidity was linked to a higher hospitalization risk, and this risk was not affected by the country's wealth and patient's gender. Multimorbidity was also linked to a higher hospital readmission rate in older adults. PROSPERO Registration (Registration number: CRD42021229328).

Indexed as

HospitalizationMultimorbidityAgedHumansMorbidityPatient Readmissionageinghospitalizationlength of staymultimorbidityolder peoplereadmission

Identifiers

PMID35871422
PMCPMC9308991
OpenAlexW4286819820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.