Evidence map›Paper›PMID 35871413›Full record

ArticleEuropean child & adolescent psychiatry2023

Developmental cascades between insistence on sameness behaviour and anxiety symptoms in autism spectrum disorder.

Danielle A Baribeau, Simone N Vigod, Eleanor Pullenayegum, Connor M Kerns, Tracy Vaillancourt, Eric Duku, Isabel M Smith, Joanne Volden, Lonnie Zwaigenbaum, Teresa Bennett and 4 more

Abstract read
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In one paragraph

Article in European child & adolescent psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Adaptive, social, and repetitive behaviors in children with autism spectrum disorder and comorbid amblyopia and/or strabismus.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2026
    Article
  4. Article
  5. What for developmentalism in psychiatry?European child & adolescent psychiatry · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Time is of the essence: Age at autism diagnosis, sex assigned at birth, and psychopathology.Autism : the international journal of research and practice · 2024
    Article
  10. Review
  11. Examining a model of anxiety in autistic adults.Autism : the international journal of research and practice · 2024
    Article
  12. Article
  13. Autism severity and its relationship to disability.Autism research : official journal of the International Society for Autism Research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 2 countries.

Danielle A BaribeauDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada. Danielle.baribeau@mail.utoronto.ca.ORCID http://orcid.org/0000-0003-4461-5851
Simone N VigodDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.
Eleanor PullenayegumThe Hospital for Sick Children, Toronto, ON, Canada.
Connor M KernsDepartment of Psychology, University of British Columbia, Vancouver, Canada.
Tracy VaillancourtCounselling Psychology, Faculty of Education, University of Ottawa, Ottawa, ON, Canada.
Eric DukuOfford Centre for Child Studies, Hamilton, ON, Canada.
Isabel M SmithDepartment of Pediatrics, Dalhousie University, Halifax, NS, Canada.
Joanne VoldenFaculty of Rehabilitation Medicine, University of Alberta, Edmonton, Canada.
Lonnie ZwaigenbaumDepartment of Pediatrics, University of Alberta, Edmonton, Canada.
Teresa BennettOfford Centre for Child Studies, Hamilton, ON, Canada.
Mayada ElsabbaghMontreal Neurological Institute, McGill University, Montreal, QC, Canada.
Anat Zaidman-ZaitDepartment of School Counseling and Special Education at the Constantiner School of Education, Tel Aviv University, Tel Aviv, Israel.
Annie E RichardAutism Research Centre, IWK Health Centre, Halifax, NS, Canada.
Peter SzatmariDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.
University of Toronto · CAMcMaster University · CAUniversity of Alberta · CAUniversity of British Columbia · CACentre for Addiction and Mental Health · CADalhousie University · CAIzaak Walton Killam Health Centre · CAMontreal Neurological Institute and Hospital · CAUniversity of Ottawa · CA

Funding

CIHR FDN 93621CIHR HDF-70333
6 · The paper itself

Abstract

Autistic children experience high rates of anxiety. Insistence on sameness behaviour (IS) is a core feature of autism that appears correlated with anxiety severity. The objective of this study was to examine the longitudinal relations between anxiety and IS in autistic children using a developmental cascade model. A longitudinal cohort of 421 autistic children was followed between 4 and 11 years of age. Anxiety was quantified using items from the Anxiety Problems subscale of the Child Behavior Checklist; sameness behaviours were measured using the Repetitive Behavior Scale-Revised, Ritualistic/sameness subscale (both parent-report measures). Structural equation modelling was used to examine the longitudinal and directional associations between anxiety and IS at four time-points, through cross-lagged panel models (CLPM) with and without a random-intercepts component (RI-CLPM). Both the CLPM and the RI-CLPM had good fit. Significant directional associations were detected whereby elevated or increasing IS preceded elevated or increasing anxiety symptoms 1-2 years later, respectively. Stable baseline tendencies towards anxiety and IS as between-person traits (intercepts) were strongly associated (standardized estimate = 0.69, p < 0.001). The magnitude of the cross-sectional associations between anxiety and IS appeared to lessen with age. IS and anxiety symptoms in autism are closely related. They appear to be shared traits that mirror each other particularly in younger children. Increasing IS may be a sign of emerging future anxiety. Interventions that target IS to reduce or prevent anxiety amongst school-aged autistic children merit further study.

Indexed as

AnxietyAutism spectrum disorderLongitudinal cohortStructural equation modelling

Identifiers

PMID35871413
OpenAlexW4286817200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.