Evidence map›Paper›PMID 35870792›Full record

ReviewBone2022

Osteoimmunology in periodontitis; a paradigm for Th17/IL-17 inflammatory bone loss.

Tomoko Ikeuchi, Niki M Moutsopoulos

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Bone, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tomoko IkeuchiOral Immunity and Infection Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, 9000 Rockville Pike, 30 convent Dr, Bldg30, Room 327, Bethesda, MD 20892, United States of America. Electronic address: tomoko.ikeuchi@nih.gov.
Niki M MoutsopoulosOral Immunity and Infection Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, 9000 Rockville Pike, 30 convent Dr, Bldg30, Room 327, Bethesda, MD 20892, United States of America. Electronic address: nmoutsop@mail.nih.gov.
National Institutes of Health · US

Funding

Intramural NIH HHS Z99 DE999999
6 · The paper itself

Abstract

Periodontitis is a prevalent human disease of inflammation-induced bone destruction. Through studies in patient lesions of rare and common forms of periodontitis and animal model experimentation, Th17/IL-17 related immune pathways have emerged as mediators of disease pathology. In this focused review, we examine mechanisms of induction, amplification and pathogenicity of Th17 cells in periodontitis.

Indexed as

Alveolar Bone LossPeriodontitisAnimalsDisease Models, AnimalHumansInflammationInterleukin-17Th17 CellsInterleukin-17Bone lossOral microbiomeOsteoimmunologyPeriodontitisTh17 cells

Identifiers

PMID35870792
PMCPMC10448972
OpenAlexW4286255725

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.