Evidence map›Paper›PMID 35870739›Full record

ArticleAlcohol (Fayetteville, N.Y.)2022

Poor subjective sleep predicts compromised quality of life but not cognitive impairment in abstinent individuals with Alcohol Use Disorder.

David Piekarski, Edith V Sullivan, Adolf Pfefferbaum, Natalie M Zahr

Open access · hybridAbstract read
In one paragraph

Article in Alcohol (Fayetteville, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Major depressive disorder-alcohol use disorder comorbidity: diagnosis, mechanisms and treatment.European archives of psychiatry and clinical neuroscience · 2026
    Review
  3. Review
  4. Review
  5. The phenotype of recovery XI: associations of sleep quality and perceived stress with discounting and quality of life in substance use recovery.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  6. Serum albumin and white matter hyperintensities.Translational psychiatry · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

David PiekarskiNeuroscience Program, SRI International, 333 Ravenswood Ave., Menlo Park, CA 94025, United States.
Edith V SullivanDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305, United States.
Adolf PfefferbaumNeuroscience Program, SRI International, 333 Ravenswood Ave., Menlo Park, CA 94025, United States.
Natalie M ZahrNeuroscience Program, SRI International, 333 Ravenswood Ave., Menlo Park, CA 94025, United States; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305, United States. Electronic address: nzahr@stanford.edu.
SRI International · USStanford University · US

Funding

CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMR01AA005965 · NIAAA · STANFORD UNIVERSITY · PI PFEFFERBAUM, ADOLF, ZAHR, NATALIE M · 1985 to 2025
$13.0M
CEREBELLAR STRUCTURE AND FUNCTION IN ALCOHOLISMR01AA010723 · NIAAA · STANFORD UNIVERSITY · PI SULLIVAN, EDITH VIONI, ZAHR, NATALIE M · 1996 to 2025
$8.3M
NIAAA NIH HHS R01 AA005965NIAAA NIH HHS R01 AA010723
6 · The paper itself

Abstract

How disrupted sleep contributes to cognitive dysfunction over the dynamic course of Alcohol Use Disorder (AUD) is an emerging topic of investigation. Here, the Pittsburgh Sleep Quality Index (PSQI) was used to evaluate subjective sleep in 90 individuals with AUD sober for an average of 3 months and in 50 healthy controls. Relative to controls, AUD individuals had higher global PSQI scores (worse sleep), higher scores on the Beck Depression Inventory (BDI-II), worse Quality of Life (QoL) indicators, and poorer performance on cognitive composite tests (executive functioning, attention and working memory, visual and verbal learning or memory). Among AUD individuals, a higher PSQI score correlated with a higher BDI-II score and worse QoL, but not with cognitive scales. Also noted in the AUD group were higher global PSQI scores in individuals also diagnosed with major depressive disorder (MDD) or generalized anxiety disorder (GAD). The four variables explained 29.8% of the variance in AUD PSQI scores. In women with AUD, the four factors explained 39.3% of the variance in PSQI scores (MDD was salient); in AUD men, the four measures explained 19.9% of the variance (QoL predominated). Together, these results suggest that poor PSQI-defined sleep does not predict cognitive performance in abstinent AUD individuals and further, that differential factors associate with poor sleep in men and women with AUD.

Indexed as

AlcoholismCognitive DysfunctionMajor Depressive DisorderSleep Initiation and Maintenance DisordersSleep Wake DisordersDepressionFemaleHumansMaleQuality of LifeSleepAlcohol Use Disorders Identification Test [AUDIT]Beck Depression Inventory [BDI-II]Cognition/cognitivePittsburgh Sleep Quality Index [PSQI]Quality of Life [QOL]

Identifiers

PMID35870739
PMCPMC9581497
OpenAlexW4286266897

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.