Evidence map›Paper›PMID 35870141›Full record

ArticleJournal of the European Academy of Dermatology and Venereology : JEADV2022

Melanoma in women of childbearing age and in pregnancy in California, 1994-2015: a population-based cohort study.

M Kiuru, Q Li, G Zhu, J R Terrell, K Beroukhim, E Maverakis, T H M Keegan

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of the European Academy of Dermatology and Venereology : JEADV, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Melanoma in pregnancy.Abdominal radiology (New York) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

M KiuruDepartment of Dermatology, University of California Davis, Sacramento, California, USA.ORCID https://orcid.org/0000-0002-7010-5516
Q LiCenter for Oncology Hematology Outcomes Research and Training (COHORT) and Division of Hematology and Oncology, University of California Davis, Sacramento, California, USA.
G ZhuDepartment of Dermatology, University of California Davis, Sacramento, California, USA.
J R TerrellDepartment of Dermatology, University of California Davis, Sacramento, California, USA.
K BeroukhimDepartment of Dermatology, University of California Davis, Sacramento, California, USA.
E MaverakisDepartment of Dermatology, University of California Davis, Sacramento, California, USA.
T H M KeeganCenter for Oncology Hematology Outcomes Research and Training (COHORT) and Division of Hematology and Oncology, University of California Davis, Sacramento, California, USA.
University of California, Davis · USUniversity of California Davis Medical Center · USXijing Hospital · CN

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
Molecular basis of melanocytic neviK23AR074530 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KIURU, MAIJA HELENA TUULIA · 2019 to 2023
$840k
CDC HHSNCCDPHP CDC HHS NU58DP006344NCI NIH HHS HHSN261201800009CNCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800015CNCI NIH HHS HHSN261201800015INCI NIH HHS HHSN261201800032CNCI NIH HHS HHSN261201800032INCI NIH HHS P30 CA093373NCI NIH HHS P30CA093373-16NIAMS NIH HHS K23 AR074530NIAMS NIH HHS K23AR074530NIH HHS
6 · The paper itself

Abstract

backgroundMelanoma is one of the most common malignancies during pregnancy. There is debate regarding the impact of pregnancy on the prognosis of melanoma. Recent large population-based studies from the United States are lacking.

objectivesTo determine the characteristics and survival of women with pregnancy-associated melanoma.

methodsThis population-based, retrospective cohort study used California Cancer Registry data linked with state-wide hospitalization and ambulatory surgery data to identify 15-44-year-old female patients diagnosed with melanoma in 1994-2015, including pregnant patients. Multivariable logistic regression compared demographic and clinical characteristics between pregnant and non-pregnant women with melanoma. Multivariable cox proportional hazards regression models assessed melanoma-specific and overall survival.

resultsWe identified 13 108 patients, of which 1406 were pregnant. Pregnancy-associated melanoma was more frequent in Hispanic compared to non-Hispanic White women. Melanoma occurring post-partum was associated with greater tumour thickness (2.01-4.00 vs. 0.01-1.00 mm, odds ratio 1.75, 95% confidence interval: 1.03-2.98). There were otherwise no significant differences between pregnant and non-pregnant women. Worse survival was associated with Asian, Black and Native American race/ethnicity (vs. non-Hispanic White), lower neighbourhood socio-economic status, public insurance, tumour site, greater tumour thickness and lymph node involvement, but not pregnancy.

conclusionsMelanoma occurring post-partum was associated with greater tumour thickness, but pregnancy status did not affect survival after melanoma. Race/ethnicity, socio-economic status and health insurance impacted survival, emphasizing the importance of reducing health disparities.

Indexed as

EthnicityMelanomaAdolescentAdultCaliforniaCohort StudiesFemaleHumansPregnancyRetrospective StudiesUnited StatesYoung Adult

Identifiers

PMID35870141
PMCPMC9560982
OpenAlexW4286762025

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.