Evidence map›Paper›PMID 35870116›Full record

ArticleJournal of surgical oncology2022

Subcostal lymph nodes: An unusual sentinel lymph node basin in cutaneous melanoma.

Katherine M Marsh, Courtney M Lattimore, Christopher L Cramer, Craig L Slingluff, Lynn T Dengel

Open access · hybridAbstract read
In one paragraph

Article in Journal of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Katherine M MarshDepartment of Surgery, University of Virginia, Charlottesville, Virginia, USA.ORCID http://orcid.org/0000-0003-1927-6210
Courtney M LattimoreDepartment of Surgery, University of Virginia, Charlottesville, Virginia, USA.ORCID http://orcid.org/0000-0002-2200-6943
Christopher L CramerDepartment of Surgery, University of Virginia, Charlottesville, Virginia, USA.
Craig L SlingluffDepartment of Surgery, University of Virginia, Charlottesville, Virginia, USA.
Lynn T DengelDepartment of Surgery, University of Virginia, Charlottesville, Virginia, USA.
University of Virginia · US

Funding

Women's Oncology Program - WONP30CA044579 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Thomas P. Loughran · 1987 to 2026
$72.1M
Cardiovascular Surgery Training ProgramT32HL007849 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI KRON, IRVING L., LAUBACH, VICTOR E · 1998 to 2025
$7.0M
Postdoctoral Training Grant for MDs in Surgical Oncology ResearchT32CA163177 · NCI · UNIVERSITY OF VIRGINIA · PI Craig Lee Slingluff, Allan Tsung · 2011 to 2026
$4.6M
NCI NIH HHS P30 CA044579NCI NIH HHS T32 CA163177NHLBI NIH HHS T32 HL007849
6 · The paper itself

Abstract

BACKGROUND AND

objectivesLymphatic drainage from subcostal nodes, along the costal groove, have not previously been characterized as sites for melanoma drainage and metastasis. This study reports a series of patients with subcostal nodes draining primary melanomas, with characterization of the sites of primary melanomas that drain to these nodes.

methodsPatients who presented to our institution between 2005 and 2020 with documented cutaneous melanoma and sentinel lymph node biopsy of a subcostal node (sentinel = S), or metastases to subcostal nodes later in clinical management (recurrent = R) were included. Patient demographics, melanoma pathology, nodal features, imaging information, surgical approaches, and outcomes data were collected.

resultsSix patients had subcostal sentinel nodes (SNs). Primary sites included the posterior trunk and lateral chest wall. Subcostal nodes were found under ribs 10-12. Subcostal SNs had at least one dimension measuring 3 mm or less. There were no surgical complications related to removing the subcostal SN.

conclusionsMelanoma can metastasize to subcostal lymph nodes and be found at the time of SN biopsy or identified at recurrence. These small nodes are fed by lymphatic channels that run in the neurovascular bundle under the ribs. When lymphatic mapping identifies a subcostal SN, it should be excised.

Indexed as

MelanomaSentinel Lymph NodeSkin NeoplasmsCutaneous Malignant MelanomaHumansLymphatic MetastasisLymph Node ExcisionLymph NodesRadionuclide ImagingSentinel Lymph Node Biopsymelanomasentinel lymph nodesubcostal lymph node

Identifiers

PMID35870116
PMCPMC9707633
OpenAlexW4286750175

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.