ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2022
Cardiovascular adjustments to cold pressor test in postmenopausal women and the impact of α1-adrenergic blockade.
Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Effects of dietary nitrate on cardiovascular reactivity in normotensive postmenopausal women.European journal of applied physiology · 2026Article
- Autonomic control of blood pressure in women: The roles of hypertension and aging.Autonomic neuroscience : basic & clinical · 2025Review
- Cold exposure and the cardiovascular system: from physiological adaptation to pathological risk.Frontiers in physiology · 2025Review
- Effects of alpha-adrenergic receptor blockade on coronary circulation in postmenopausal women.European journal of applied physiology · 2023Article
- Greater resting muscle sympathetic nerve activity reduces cold pressor autonomic reactivity in older women, but not older men.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Article
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Authors and funding
5 authors.
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Abstract
purposeWe investigate the impact of menopause on cardiovascular adjustments to the cold pressor test (CPT) and the role of the α1-adrenergic receptor.
methodsTen young women (YW) and nine postmenopausal women (MW) underwent 1 min of CPT in control and α1-blockade conditions (0.03 mg‧kg
resultsCPT increased heart rate (HR) (YW: ∆20 ± 3 bpm; MW: ∆13 ± 2 bpm) and stroke volume (SV; YW: ∆15 ± 8 ml; MW: ∆9 ± 6 ml; p = 0.01 for time) and evoked a greater increase in cardiac output (CO) in YW (YW: ∆2.1 ± 0.2 l‧m
conclusionIn postmenopausal women, the cardiac ability to adjust to CPT is blunted and α1-adrenergic receptor stimulation is important for the increase in stroke volume. In addition, the peripheral effect of α1-adrenergic receptor stimulation seems to be increased in postmenopausal women.
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