Evidence map›Paper›PMID 35869956›Full record

ArticleJournal of clinical psychology2023

Intergenerational transmission of lifetime stressor exposure in adolescent girls at differential maternal risk for depression.

Michael L M Murphy, Stassja Sichko, Theresa Q Bui, Mark R Libowitz, Grant S Shields, George M Slavich

Abstract read
In one paragraph

Article in Journal of clinical psychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael L M MurphyDepartment of Psychological Sciences, Texas Tech University, Lubbock, Texas, USA.ORCID 0000-0001-7776-3186
Stassja SichkoDepartment of Psychology, University of California, Los Angeles, California, USA.
Theresa Q BuiTulane University School of Medicine, New Orleans, Louisiana, USA.
Mark R LibowitzDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California, USA.
Grant S ShieldsDepartment of Psychological Science, University of Arkansas, Fayetteville, Arkansas, USA.
George M SlavichDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California, USA.ORCID 0000-0001-5710-3818

Funding

Neural, Inflammatory, and Genomic Mechanisms Underlying Risk for Depression in AdolescenceK08MH103443 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SLAVICH, GEORGE MICHAEL · 2015 to 2018
$772k
NIMH NIH HHS K08 MH103443
6 · The paper itself

Abstract

objectiveAdolescent girls who grow up with mothers who are depressed are themselves highly vulnerable to developing depression (i.e., "intergenerational transmission of depression"). Stressor exposure is a strong risk factor for depression, and the transmission of depression risk from mothers to daughters is partly due to mothers experiencing more stressors, increasing daughters' stressor burden. However, research in this area has only assessed recent stressors, making the role of cumulative lifetime stressors unclear.

methodTo address this issue, we recruited 52 dyads of mothers and adolescent daughters, of which 22 daughters were at high maternal risk for depression. Participants completed diagnostic interviews, and daughters additionally self-reported their depressive symptoms. Participants also completed the Stress and Adversity Inventory, a new-generation instrument for assessing cumulative lifetime history of acute and chronic stressors based on the contextual threat approach. We tested moderated mediation models evaluating the conditional indirect effects of mothers' lifetime stressors on high- versus low-risk daughters' depressive symptoms through daughters' lifetime stressors.

resultsAs hypothesized, mothers of high-risk (but not low-risk) adolescent daughters who reported more lifetime acute stressors had daughters who reported more lifetime acute stressors and current depressive symptoms. Moreover, this finding was driven specifically by mothers' stressors occurring after their daughters' births. There was also tentative evidence that high-risk daughters' lifetime chronic stressors potentiated the impact of daughters' acute stressors on their depressive symptoms.

conclusionThese findings provide new insights into how stressful contexts are transmitted intergenerationally.

Indexed as

DepressionMothersAdolescentFemaleHumansMother-Child RelationsNuclear FamilyRisk FactorsSelf Reportadolescencedepressionenvironmental influencesfamily historystress

Identifiers

PMID35869956
PMCPMC9851932

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.