Evidence map›Paper›PMID 35869601›Full record

ArticleCancer reports (Hoboken, N.J.)2022

Safe performance of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with HIV infection.

Anna Coghill, Julian Sanchez, Sweta Sinha, Jennifer B Permuth, Danielle Laskowitz, Benjamin D Powers, Sean P Dineen

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anna CoghillCenter for Immunization and Infection Research in Cancer, Moffitt Cancer Center, Tampa, Florida, USA.
Julian SanchezDepartment of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Sweta SinhaCancer Epidemiology Program, Moffitt Cancer Center, Tampa, Florida, USA.
Jennifer B PermuthCancer Epidemiology Program, Moffitt Cancer Center, Tampa, Florida, USA.
Danielle LaskowitzDepartment of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Benjamin D PowersDepartment of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.ORCID 0000-0003-2679-6302
Sean P DineenDepartment of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.ORCID 0000-0002-2012-2238
University of South Florida · USMoffitt Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with HIV (PHIV) are living longer with the adoption of anti-retroviral therapy. As such, more patients are presenting with advanced cancer diagnoses, including peritoneal surface malignancies. The objective of this study was to assess the safety of CRS/HIPEC in this cohort of patients. CASE: Five PHIV were identified, four of whom underwent CRS/HIPEC. Primary sites of disease were low-grade appendiceal mucinous tumors in three patients and peritoneal mesothelioma in the other. Operative time ranged from 7 to 14 h. One patient developed a Clavien grade II complication postoperatively. There was no instance of neutropenia identified. One patient died of disease 19 months after surgery; the remaining three patients are alive 11, 21, and 33 months postoperatively.

conclusionThis study demonstrates that CRS/HIPEC can be performed in PHIV without prohibitive complications and operative recovery approximates that of non-HIV patients. Though more study is needed, HIV should not preclude a patient from being offered CRS/HIPEC.

Indexed as

HIV InfectionsHyperthermia, InducedPeritoneal NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsCytoreduction Surgical ProceduresHumansHyperthermic Intraperitoneal ChemotherapySurvival RateGI surgeryHIPEC procedureHIV and cancerHIV oncology

Identifiers

PMID35869601
PMCPMC9575487
OpenAlexW4286686389

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.