SynthesisAlzheimer's research & therapy2022
Grey matter changes on brain MRI in subjective cognitive decline: a systematic review.
Synthesis in Alzheimer's research & therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- Multiscale Approximations to Understand the Complex Role of Microglia in Alzheimer's Disease.The European journal of neuroscience · 2026Review
- Characterizing olfaction, anxiety, and depression in subjective cognitive decline.Journal of Alzheimer's disease : JAD · 2026Article
- Article
- Predicting the progression of MCI and Alzheimer's disease on structural brain integrity and other features with machine learning.GeroScience · 2026Article
- Disentangling Neurodegeneration with Brain Age Gap Prediction Models: A Graph Signal Processing Perspective.ArXiv · 2025Article
- Subjective cognitive decline in individuals with isolated REM sleep behavior disorder.NPJ Parkinson's disease · 2025Article
- Cognitive reserve in subjective cognitive decline with worry: DMN-VN connectivity supports episodic memory under structural vulnerability.BMC geriatrics · 2025Article
- Hybrid multi-modality multi-task learning for forecasting progression trajectories in subjective cognitive decline.Neural networks : the official journal of the International Neural Network Society · 2025Article
- CD-Tron: Leveraging large clinical language model for early detection of cognitive decline from electronic health records.Journal of biomedical informatics · 2025Article
- Digital twins and non-invasive recordings enable early diagnosis of Alzheimer's disease.Alzheimer's research & therapy · 2025Observational
- CD-Tron: Leveraging Large Clinical Language Model for Early Detection of Cognitive Decline from Electronic Health Records.medRxiv : the preprint server for health sciences · 2025Article
- Heterogeneous brain abnormalities in subjective cognitive decline converge on a common network and their transcriptional signature.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Expression of Neuronal Nicotinic Acetylcholine Receptor and Early Oxidative DNA Damage in Aging Rat Brain-The Effects of Memantine.International journal of molecular sciences · 2025Article
- Sex-specific brain morphological and network differences in patients showing Parkinson's disease with and without possible rapid eye movement sleep behavior disorder.Frontiers in neurology · 2025Article
- Brain structure, amyloid, and behavioral features for predicting clinical progression in subjective cognitive decline.Human brain mapping · 2024Article
- Comprehensive assessment of sleep duration, insomnia, and brain structure within the UK Biobank cohort.Sleep · 2024Article
- Impact of repetitive negative thinking on subjective cognitive decline: insights into cognition and brain structure.Frontiers in aging neuroscience · 2024Article
- Clinically feasible automated MRI volumetry of the brain as a prognostic marker in subjective and mild cognitive impairment.Frontiers in neurology · 2024Article
- Altered cortical and subcortical morphometric features and asymmetries in the subjective cognitive decline and mild cognitive impairment.Frontiers in neurology · 2023Article
- Subjective cognitive complaints in White and African American older adults: associations with demographic, mood, cognitive, and neuroimaging features.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognitionArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPeople with subjective cognitive decline (SCD) report cognitive deterioration. However, their performance in neuropsychological evaluation falls within the normal range. The present study aims to analyse whether structural magnetic resonance imaging (MRI) reveals grey matter changes in the SCD population compared with healthy normal controls (HC).
methodsParallel systematic searches in PubMed and Web of Science databases were conducted, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Quality assessment was completed using the Newcastle-Ottawa Scale (NOS).
resultsFifty-one MRI studies were included. Thirty-five studies used a region of interest (ROI) analysis, 15 used a voxel-based morphometry (VBM) analysis and 10 studies used a cortical thickness (CTh) analysis. Ten studies combined both, VBM or CTh analysis with ROI analysis.
conclusionsMedial temporal structures, like the hippocampus or the entorhinal cortex (EC), seemed to present grey matter reduction in SCD compared with HC, but the samples and results are heterogeneous. Larger sample sizes could help to better determine if these grey matter changes are consistent in SCD subjects.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.