Evidence map›Paper›PMID 35869453›Full record

ArticleBMC musculoskeletal disorders2022

Effect of knee joint weight change on knee function recovery and gait after total knee arthroplasty.

Zhengya Zhu, Tao Tang, Sheng Pan, Ziqian Sun, Chaoran Huang, Ruxin Ruan, Zhongyuan He, Shaoyu Liu, Xin Zheng, Kaijin Guo

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Zhengya Zhu *Department of Orthopaedics, Seventh Affiliated Hospital of Sun Yat-Sen University, 628 Zhenyuan Road, Shenzhen, 518107, People's Republic of China.
Tao Tang *Department of Orthopaedics, Seventh Affiliated Hospital of Sun Yat-Sen University, 628 Zhenyuan Road, Shenzhen, 518107, People's Republic of China.
Sheng PanDepartment of Orthopaedics, Affiliated Hospital of Xuzhou Medical University, 99 Huaihai West Road, Xuzhou, 221006, People's Republic of China.
Ziqian SunDepartment of Oncology, Xuzhou Cancer Hospital, Huancheng Road, Xuzhou, 221006, People's Republic of China.
Chaoran HuangDepartment of Orthopaedics, Affiliated Hospital of Xuzhou Medical University, 99 Huaihai West Road, Xuzhou, 221006, People's Republic of China.
Ruxin RuanDepartment of Orthopaedics, Affiliated Hospital of Xuzhou Medical University, 99 Huaihai West Road, Xuzhou, 221006, People's Republic of China.
Zhongyuan HeDepartment of Orthopaedics, Seventh Affiliated Hospital of Sun Yat-Sen University, 628 Zhenyuan Road, Shenzhen, 518107, People's Republic of China.
Shaoyu LiuDepartment of Orthopaedics, Seventh Affiliated Hospital of Sun Yat-Sen University, 628 Zhenyuan Road, Shenzhen, 518107, People's Republic of China.
Xin ZhengDepartment of Orthopaedics, Zhujiang Hospital of Southern Medical University, 253 Gongye Avenue, Guangzhou, 510282, People's Republic of China. drzhengxin@163.com.
Kaijin GuoDepartment of Orthopaedics, Affiliated Hospital of Xuzhou Medical University, 99 Huaihai West Road, Xuzhou, 221006, People's Republic of China. kaijinguo@163.com.
Xuzhou Medical College · CNSun Yat-sen University · CNThe Seventh Affiliated Hospital of Sun Yat-sen University · CNJiangsu University · CNZhujiang Hospital · CN

Funding

Jiangsu Provincial Medical Youth Talent QNRC2016801National Natural Science Foundation of China 81902244Natural Science Foundation of Jiangsu Province BK20201154Xuzhou Science and Technology Innovation Project KC19063
6 · The paper itself

Abstract

backgroundKnee osteoarthritis (KOA) is a common disease based on degenerative pathological changes. Total knee arthroplasty (TKA) is an effective treatment for end-stage of KOA. However, only volume adaptation can be achieved with current knee prostheses, and it is difficult to achieve weight adaptation. This study focused on the weight difference of knee joints and initially explored the impact of this change on knee joint functional recovery and gait changes in patients after surgery.

methodsFrom October 2015 to June 2019, patients who underwent primary unilateral TKA were enrolled in this prospective cohort study with the same brand of knee prostheses. General data were collected from patients who met the criteria. The resected bone and soft tissues were collected and weighed precisely during TKA, and multivariate regression analysis was used to determine the factors affecting the weight of the removed knee tissues. We compared the weight of excised tissues and the total weight of the knee prosthesis, and the weight difference was defined as the increased weight of the knee joint (IWKJ). All patients were evaluated by HSS score, gait analysis, and affected side knee X-ray at two weeks, three months, and the last follow-up after the operation. To further determine the influence of IWKJ on postoperative functional recovery, the relationship between IWKJ, HSS score, and gait analysis was analyzed by univariate regression.

resultsIn total, 210 patients were eventually included in observation. All patients underwent postoperative follow-up for no less than two years. Multiple regression analysis showed that the course of the disease, body weight, and kellgren-Larencen stage(K-L stage)of the affected knee joint were independent factors affecting the weight of the removed knee tissues and were positively correlated with it. Univariate analysis showed that IWKJ was negatively correlated with HSS score at two weeks and three months after the operation. In addition, the values of spatiotemporal parameters and knee rotation ROM were negatively correlated with IWKJ two weeks after surgery, while outside food load response was positively correlated with IWKJ. Cadence, knee rotation ROM, and Ankle rotation ROM were negatively correlated with IWKJ, while outside food was positively correlated with IWKJ three months after surgery. At the last follow-up, only the hip rotation ROM was positively correlated with IWKJ.

conclusionsAll Patients underwent TKA had varying degrees of increased knee weight. The increased weight was 298.98 ± 63.77 g. Patients' body weight, K-L staging, and disease duration are important factors that cause differences in resected knee tissue. Three months after the operation, the changes in knee joint weight had a negative correlation with the HSS score, which at the same time, it had varying degrees of linearity with gait parameters. However, the influence of weight diminished over time.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisOsteoarthritis, KneeBody WeightGaitHumansKnee JointProspective StudiesRange of Motion, ArticularRecovery of FunctionTreatment OutcomeGaitHSS ScoreTotal knee arthroplasty, prosthesis, weight

Identifiers

PMID35869453
PMCPMC9306069
OpenAlexW4286433203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.