Evidence map›Paper›PMID 35869436›Full record

ArticleBMC nephrology2022

Living with frailty and haemodialysis: a qualitative study.

Hannah M L Young, Nicki Ruddock, Mary Harrison, Samantha Goodliffe, Courtney J Lightfoot, Juliette Mayes, Andrew C Nixon, Sharlene A Greenwood, Simon Conroy, Sally J Singh and 3 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07377500 (Randomised Controlled Trial of Dialysate Cooling for the Preservation of Cognitive Function in People Receiving Haemodialysis), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07377500 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Randomised Controlled Trial of Dialysate Cooling for the Preservation of Cognitive Function in People Receiving Haemodialysis

TypeinterventionalSponsorUniversity Hospitals of Derby and Burton NHS Foundation TrustRan2026 to 2028Enrolled356ConditionsHaemodialysis, Kidney FailureArmsDialysis cooling
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Hannah M L YoungLeicester Diabetes Centre, University Hospitals of Leicester NHS Trust, Leicester, England. hy162@le.ac.uk.
Nicki RuddockJohn Walls Renal Unit, University Hospitals of Leicester NHS Trust, Leicester, England.
Mary HarrisonLeicester Diabetes Centre, University Hospitals of Leicester NHS Trust, Leicester, England.
Samantha GoodliffeSchool of Health, Wellbeing and Social Care, The Open University, Milton Keynes, England.
Courtney J LightfootDepartment of Health Sciences, University of Leicester, Leicester, England.
Juliette MayesDepartment of Physiotherapy and Renal Medicine, King's College Hospital and Department of Renal Medicine, King's College London, London, England.
Andrew C NixonDepartment of Renal Medicine, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
Sharlene A GreenwoodDepartment of Physiotherapy and Renal Medicine, King's College Hospital and Department of Renal Medicine, King's College London, London, England.
Simon ConroyCentral and North West London NHS Foundation Trust - MRC Unit for Lifelong Health and Ageing, University College London, London, England.
Sally J SinghCentre for Exercise & Rehabilitation Science, NIHR Leicester Biomedical Research Centre, Leicester, England.
James O BurtonDepartment of Cardiovascular Sciences, University of Leicester, Leicester, England.
Alice C SmithDepartment of Health Sciences, University of Leicester, Leicester, England.
Helen EborallUsher Institute, University of Edinburgh, Edinburgh, Scotland.
University of Leicester · GBUniversity Hospitals of Leicester NHS Trust · GBKing's College Hospital · GBKing's College London · GBLancashire Teaching Hospitals NHS Foundation Trust · GBNIHR Leicester Biomedical Research Centre · GBThe Open University · GBUniversity College London · GBUniversity of Edinburgh · GB

Funding

Department of HealthMedical Research Council MC_UU_00019/2Medical Research Council MC_UU_00019/4
6 · The paper itself

Abstract

backgroundFrailty is highly prevalent in people receiving haemodialysis (HD) and is associated with poor outcomes. Understanding the lived experiences of this group is essential to inform holistic care delivery.

methodsSemi-structured interviews with N = 25 prevalent adults receiving HD from 3 HD units in the UK. Eligibility criteria included a Clinical Frailty Scale (CFS) score of 4-7 and a history of at least one fall in the last 6 months. Sampling began guided by maximum variation sampling to ensure diversity in frailty status; subsequently theoretical sampling enabled exploration of preliminary themes. Analysis was informed by constructivist grounded theory; later we drew upon the socioecological model.

resultsParticipants had a mean age of 69 ± 10 years, 13 were female, and 13 were White British. 14 participants were vulnerable or mildly frail (CFS 4-5), and 11 moderately or severely frail (CFS 6-7). Participants characterised frailty as weight loss, weakness, exhaustion, pain and sleep disturbance arising from multiple long-term conditions. Participants' accounts revealed: the consequences of frailty (variable function and psychological ill-health at the individual level; increasing reliance upon family at the interpersonal level; burdensome health and social care interactions at the organisational level; reduced participation at the community level; challenges with financial support at the societal level); coping strategies (avoidance, vigilance, and resignation); and unmet needs (overprotection from family and healthcare professionals, transactional health and social care exchanges).

conclusionsThe implementation of a holistic needs assessment, person-centred health and social care systems, greater family support and enhancing opportunities for community participation may all improve outcomes and experience. An approach which encompasses all these strategies, together with wider public health interventions, may have a greater sustained impact.

trial registrationISRCTN12840463 .

Indexed as

FrailtyAdultAgedFemaleFrail ElderlyHumansMaleMiddle AgedQualitative ResearchRenal DialysisDialysisFrailtyHaemodialysisInterviewsMulti-morbidityPatient experienceQualitative

Identifiers

PMID35869436
PMCPMC9308309
OpenAlexW4286586263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.