ArticleThe ISME journal2022
Small changes in rhizosphere microbiome composition predict disease outcomes earlier than pathogen density variations.
Article in The ISME journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
70 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.
- Bacillus species as tools for biocontrol of plant diseases: A meta-analysis of twenty-two years of research, 2000-2021.World journal of microbiology & biotechnology · 2024Pooled it
- Wild rice locus enables microbiome re-domestication for enhanced nitrogen-use efficiency.Nature microbiology · 2026Article
- Enhanced Endophytic Colonization of Flavobacterium Promotes Plant Resistance to Fusarium Wilt.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Ecological Management of Crown Gall-Affected Soils: Pathogen Reservoirs, Disease-Suppressive Microbiomes, and Helper Consortia.Microorganisms · 2026Review
- It takes a village: how plant-associated bacterial communities socialise to shape plant growth and health.Essays in biochemistry · 2026Review
- Beyond detection: unveiling microbial dynamics in oak seedlings using fungal isolation and amplicon sequencing.Environmental microbiome · 2026Article
- Rhizoplane microbiome: niche-specific recruitment and plant defense priming against bacterial wilt disease.Plant physiology · 2026Article
- Biocontrol Microbial Inoculants SuppressPlants (Basel, Switzerland) · 2026Article
- Pathogenicity of Cadophora luteo-olivacea on Quercus robur and multi-omics characterization of antagonism by Trichoderma atroviride.Scientific reports · 2026Article
- Diversity, Composition and Resilience of the Root Microbiome of Tomato Plants in a Hydroponic Rockwool System.Environmental microbiology reports · 2026Article
- Microbial Community Shifts and Plant Performance Improvements Driven by Bacillus firmus in Pampa Agroecosystems.Environmental microbiology reports · 2026Article
- Herbicide Application Under Co-Cultivation Is Associated with Early Microbiome Assembly Shifts and Later Physiological Decline in Rice.Microorganisms · 2026Article
- Anthracnose drives assembly of phyllosphere epiphytic bacterial communities to increase disease resistance.NPJ biofilms and microbiomes · 2026Article
- From triangle to pyramid: Understanding host-pathogen-microniome-environment interplay for sustainable, enviromics-empowered management of plant diseases.Plant communications · 2026Review
- Article
- Forecasting Root Rot Disease through Predictive Microbial Functional Profiling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Phenolic acid biosynthesis is associated with deleterious microbiome changes during Plasmodiophora brassicae-induced clubroot in pakchoi.Microbiome · 2026Article
- Differential Selection Effects of Continuous AITC Fumigation on Soil Microbial Communities and Functions and Identification of Tolerant Strains.Microorganisms · 2026Article
- Metagenomic sequencing reveals structural and functional differentiation of rhizosphere bacterial communities driven by nitrogen and potassium deficiency associated with root rot ofFrontiers in microbiology · 2026Article
- Metagenomic sequencing reveals structural and functional differentiation of the rhizosphere bacterial communities associated with available potassium inFrontiers in microbiology · 2026Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Even in homogeneous conditions, plants facing a soilborne pathogen tend to show a binary outcome with individuals either remaining fully healthy or developing severe to lethal disease symptoms. As the rhizosphere microbiome is a major determinant of plant health, we postulated that such a binary outcome may result from an early divergence in the rhizosphere microbiome assembly that may further cascade into varying disease suppression abilities. We tested this hypothesis by setting up a longitudinal study of tomato plants growing in a natural but homogenized soil infested with the soilborne bacterial pathogen Ralstonia solanacearum. Starting from an originally identical species pool, individual rhizosphere microbiome compositions rapidly diverged into multiple configurations during the plant vegetative growth. This variation in community composition was strongly associated with later disease development during the later fruiting state. Most interestingly, these patterns also significantly predicted disease outcomes 2 weeks before any difference in pathogen density became apparent between the healthy and diseased groups. In this system, a total of 135 bacterial OTUs were associated with persistent healthy plants. Five of these enriched OTUs (Lysinibacillus, Pseudarthrobacter, Bordetella, Bacillus, and Chryseobacterium) were isolated and shown to reduce disease severity by 30.4-100% when co-introduced with the pathogen. Overall, our results demonstrated that an initially homogenized soil can rapidly diverge into rhizosphere microbiomes varying in their ability to promote plant protection. This suggests that early life interventions may have significant effects on later microbiome states, and highlights an exciting opportunity for microbiome diagnostics and plant disease prevention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.