Evidence map›Paper›PMID 35868821›Full record

ArticleBMJ open2022

Prehospital care for ovarian cancer in Catalonia: could we do better in primary care? Retrospective cohort study.

Carmen Vela-Vallespín, Paula Manchon-Walsh, Luisa Aliste, Josep M Borras, Mercè Marzo-Castillejo

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Women's experiences along the ovarian cancer diagnostic pathway in Catalonia: A qualitative study.Health expectations : an international journal of public participation in health care and health policy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Carmen Vela-VallespínPrimary Health Care Center Riu Nord i Riu Sud, Catalan Institute of Health, Santa Coloma de Gramenet, Spain.
Paula Manchon-WalshCatalonian Cancer Strategy, Department of Health, L'Hospitalet de Llobregat, Spain.
Luisa AlisteCatalonian Cancer Strategy, Department of Health, L'Hospitalet de Llobregat, Spain.
Josep M BorrasCatalonian Cancer Strategy, Department of Health, L'Hospitalet de Llobregat, Spain.
Mercè Marzo-CastillejoResearch Support Unit Metropolitana Sud, University Institute for Primary Health Care Research (IDIAP) Jordi Gol, Catalan Health Institut, Cornellà de Llobregat, Spain mmarzoc@gencat.cat.ORCID 0000-0002-1201-3090
Cornell University · USInstitut Universitari d'Investigació en Atenció Primària Jordi Gol · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the impact of prehospital factors (diagnostic pathways, first presentation to healthcare services, intervals, participation in primary care) on 1-year and 5-year survival in people with epithelial ovarian cancer (EOC).

designRetrospective quasi-population-based cohort study.

settingCatalan Integrated Public Healthcare System.

participantsPeople with EOC who underwent surgery with a curative intent in public Catalan hospitals between 1 January 2013 and 31 December 2014. OUTCOME MEASURES: Data from primary and secondary care clinical histories and care processes in the 18 months leading up to confirmation (signs and symptoms at presentation, diagnosis pathways, referrals, diagnosis interval) of the EOC diagnosis (stage, histology type, treatment). Diagnostic process intervals were based on the Aarhus statement. 1-year and 5-year survival analysis was undertaken.

resultsOf the 513 patients included in the cohort, 67.2% initially consulted their family physician, while 36.4% were diagnosed through emergency services. In the Cox models, survival was influenced by advanced stage at 1 year (HR 3.84, 95% CI 1.23 to 12.02) and 5 years (HR 5.36, 95% CI 3.07 to 9.36), as was the type of treatment received, although this association was attenuated over follow-up. Age became significant at 5 years of follow-up. After adjusting for age, adjusted morbidity groups, stage at diagnosis and treatment, 5-year survival was better in patients presenting with gynaecological bleeding (HR 0.35, 95% CI 0.16 to 0.79). Survival was not associated with a starting point involving primary care (HR 1.39, 95% CI 0.93 to 2.09), diagnostic pathways involving referral to elective gynaecological care from non-general practitioners (HR 0.80, 95% CI 0.51 to 1.26), or self-presentation to emergency services (HR 0.82, 95% CI 0.52 to 1.31).

conclusionsSurvival in EOC is not associated with diagnostic pathways or prehospital healthcare, but it is influenced by stage at diagnosis, administration of primary cytoreduction plus chemotherapy and patient age.

Indexed as

Emergency Medical ServicesNeoplasms, Glandular and EpithelialOvarian NeoplasmsCarcinoma, Ovarian EpithelialChild, PreschoolCohort StudiesFemaleHumansPrimary Health CareRetrospective StudiesSpainAUDITGynaecological oncologyPRIMARY CARE

Identifiers

PMID35868821
PMCPMC9316044
OpenAlexW4286566110

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.