Evidence map›Paper›PMID 35868337›Full record

ArticleEmerging infectious diseases2022

Longitudinal SARS-CoV-2 Nucleocapsid Antibody Kinetics, Seroreversion, and Implications for Seroepidemiologic Studies.

Michael Loesche, Elizabeth W Karlson, Opeyemi Talabi, Guohai Zhou, Natalie Boutin, Rachel Atchley, Gideon Loevinsohn, Jun Bai Park Chang, Mohammad A Hasdianda, Adetoun Okenla and 10 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 1 country.

Michael Loesche
Elizabeth W Karlson
Opeyemi Talabi
Guohai Zhou
Natalie Boutin
Rachel Atchley
Gideon Loevinsohn
Jun Bai Park Chang
Mohammad A Hasdianda
Adetoun Okenla
Elizabeth Sampson
Haley Schram
Karen Magsipoc
Kirsten Goodman
Lauren Donahue
Maureen MacGowan
Lewis A Novack
Petr Jarolim
Lindsey R Baden
Eric J Nilles
Massachusetts General Hospital · USHarvard University · USBrigham and Women's Hospital · USDana-Farber/Harvard Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given widespread use of spike antibody in generating coronavirus disease vaccines, SARS-CoV-2 nucleocapsid antibodies are increasingly used to indicate previous infection in serologic surveys. However, longitudinal kinetics and seroreversion are poorly defined. We found substantial seroreversion of nucleocapsid total immunoglobulin, underscoring the need to account for seroreversion in seroepidemiologic studies.

Indexed as

COVID-19SARS-CoV-2Antibodies, ViralCoronavirus Nucleocapsid ProteinsHumansKineticsNucleocapsidPhosphoproteinsSeroepidemiologic StudiesAntibodies, ViralCoronavirus Nucleocapsid Proteinsnucleocapsid phosphoprotein, SARS-CoV-2Phosphoproteinscoronavirus diseasecoronavirusesCOVID-19kineticslongitudinalnucleocapsid antibodyrespiratory infectionsSARS-CoV-2seroepidemiologyseroreversionsevere acute respiratory syndrome coronavirus 2viruseszoonoses

Identifiers

PMID35868337
PMCPMC9423917
OpenAlexW4286602746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.