Evidence map›Paper›PMID 35868255›Full record

ArticleMolecular cell2022

You shall not pass! Unveiling the barriers for cohesin-mediated loop extrusion.

Silvia Meyer-Nava, Juan Carlos Rivera-Mulia

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Silvia Meyer-NavaDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN, USA; Stem Cell Institute, University of Minnesota Medical School, Minneapolis, MN, USA.
Juan Carlos Rivera-MuliaDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN, USA; Stem Cell Institute, University of Minnesota Medical School, Minneapolis, MN, USA; Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN, USA. Electronic address: riveramj@umn.edu.
University of Minnesota · US

Funding

Regulatory elements of replication timing and 3D genome organizationR35GM137950 · NIGMS · UNIVERSITY OF MINNESOTA · PI RIVERA-MULIA, JUAN CARLOS · 2020 to 2024
$2.3M
Austrian Science Fund FWF P 30613Medical Research Council MC_UU_00007/2NIGMS NIH HHS R35 GM137950
6 · The paper itself

Abstract

Dequeker and colleagues performed elegant in vivo, in silico, and in vitro experiments to demonstrate that the MCM complex, an essential DNA replication factor, is an obstacle for the DNA loop formation by cohesin.

Indexed as

Cell Cycle ProteinsChromosomal Proteins, Non-HistoneCell NucleusChromatinCohesinsCell Cycle ProteinsChromatinChromosomal Proteins, Non-HistoneCohesins

Identifiers

PMID35868255
PMCPMC9989844
OpenAlexW4286449008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.