Evidence map›Paper›PMID 35868151›Full record

ArticleThrombosis research2022

Impact of pharmacist intervention on anticoagulation management and risk for potential COVID-19 exposure during the COVID-19 pandemic.

Lindsey C Lee, Phillip Farwig, Lauren Kirk, Virginia D Mitchell, Jennifer A Sabatino, Kelli D Barnes

Open access · greenAbstract read
In one paragraph

Article in Thrombosis research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lindsey C LeeThe Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America; The Ohio State University College of Pharmacy, 500 W. 12th Avenue, Columbus, OH 43210, United States of America. Electronic address: Lee.8791@osu.edu.
Phillip FarwigThe Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America. Electronic address: Phillip.Farwig@osumc.edu.
Lauren KirkThe Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America. Electronic address: Lauren.Kirk@osumc.edu.
Virginia D MitchellThe Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America. Electronic address: Virginia.Mitchell@osumc.edu.
Jennifer A SabatinoThe Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America. Electronic address: Jennifer.Sabatino@osumc.edu.
Kelli D BarnesThe Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America. Electronic address: Kelli.Barnes2@osumc.edu.
The Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients taking warfarin require frequent international normalized ratio (INR) monitoring in healthcare settings, putting them at increased risk of Coronavirus disease 2019 (COVID-19) exposure during the pandemic. Thus, strategies to limit in-person visits to healthcare facilities were recommended by the Anticoagulation Forum. The objective of this study was to describe the number and types of changes made to anticoagulation therapy as a result of pharmacist intervention during the COVID-19 pandemic. MATERIALS AND

methodsA retrospective chart review of patients included in a primary care COVID-19 anticoagulation intervention was conducted. During this intervention, pharmacists provided individualized recommendations for anticoagulation changes in patients taking warfarin to limit their healthcare facility exposure while also maintaining safe anticoagulation management practices.

resultsAs a result of pharmacist intervention, 83 (55.7 %) of the 149 patients included in the intervention had changes in anticoagulation including: switching to a direct oral anticoagulant (n = 12), extending the INR monitoring interval (n = 48), switching to home INR monitoring (n = 21), or stopping anticoagulation (n = 2). For those patients who were taking warfarin for the entire 6 months pre- and post-intervention, the total number of healthcare facility and laboratory visits with an INR completed decreased from 8.8 to 6.4 (p < 0.001) per patient without a statistically significant decrease in time in therapeutic range (p = 0.76).

conclusionsThis study depicts rapid implementation of a population health-based approach to assess all patients taking warfarin for options to minimize healthcare visits and decrease risk for COVID-19 exposure. Methods to reduce healthcare visit burden while maintaining patient safety should be considered as a regular component of anticoagulation management post-pandemic.

Indexed as

COVID-19WarfarinAnticoagulantsDrug MonitoringHumansInternational Normalized RatioPandemicsPharmacistsRetrospective StudiesAnticoagulantsWarfarinAnticoagulationCOVID-19Direct oral anticoagulant (DOAC)PharmacistPopulation healthWarfarin

Identifiers

PMID35868151
PMCPMC9288238
OpenAlexW4285678558

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.