Evidence map›Paper›PMID 35867934›Full record

ArticleACS applied materials & interfaces2022

TiO

Jiajun Luo, Shudong Zhao, Xiangsheng Gao, Swastina Nath Varma, Wei Xu, Maryam Tamaddon, Richard Thorogate, Haoran Yu, Xin Lu, Manuel Salmeron-Sanchez and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Jiajun LuoDivision of Surgery & Interventional Science, Royal National Orthopaedic Hospital, University College London, Stanmore HA7 4LP, U.K.ORCID 0000-0003-4735-102X
Shudong ZhaoDivision of Surgery & Interventional Science, Royal National Orthopaedic Hospital, University College London, Stanmore HA7 4LP, U.K.
Xiangsheng GaoDivision of Surgery & Interventional Science, Royal National Orthopaedic Hospital, University College London, Stanmore HA7 4LP, U.K.
Swastina Nath VarmaDivision of Surgery & Interventional Science, Royal National Orthopaedic Hospital, University College London, Stanmore HA7 4LP, U.K.ORCID 0000-0002-9449-8772
Wei XuDivision of Surgery & Interventional Science, Royal National Orthopaedic Hospital, University College London, Stanmore HA7 4LP, U.K.
Maryam TamaddonDivision of Surgery & Interventional Science, Royal National Orthopaedic Hospital, University College London, Stanmore HA7 4LP, U.K.
Richard ThorogateLondon Centre for Nanotechnology, University College London, London WC1H 0AH, U.K.
Haoran YuInstitute of Bioengineering, College of Chemical and Biological Engineering, Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 310027, China.
Xin LuBeijing Advanced Innovation Center for Materials Genome Engineering, Institute for Advanced Materials and Technology, State Key Laboratory for Advanced Metals and Materials, University of Science and Technology Beijing, Beijing 100083, China.
Manuel Salmeron-SanchezCentre for the Cellular Microenvironment, University of Glasgow, Glasgow G12 8LT, U.K.ORCID 0000-0002-8112-2100
Chaozong LiuDivision of Surgery & Interventional Science, Royal National Orthopaedic Hospital, University College London, Stanmore HA7 4LP, U.K.
Royal National Orthopaedic Hospital · GBLondon Centre for Nanotechnology · GBUniversity of Glasgow · GBUniversity of Science and Technology Beijing · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotopography is an effective method to regulate cells' behaviors to improve Ti orthopaedic implants' in vivo performance. However, the mechanism underlying cellular matrix-nanotopography interactions that allows the modulation of cell adhesion has remained elusive. In this study, we have developed novel nanotopographic features on Ti substrates and studied human osteoblast (HOb) adhesion on nanotopographies to reveal the interactive mechanism regulating cell adhesion and spreading. Through nanoflat, nanoconvex, and nanoconcave TiO

Indexed as

OsteoblastsTitaniumCell AdhesionFocal AdhesionsHumansSurface PropertiesTitaniumtitanium dioxidecell adhesioncell−material interactionnanotopographyprotein adsorptionTi implant

Identifiers

PMID35867934
PMCPMC9354007
OpenAlexW4286602923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.